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Family Rubiaceae
Dona Trining
Mussaenda erythrophylla Schum. & Thonn.
RED FLAG BUSH

Scientific names Common names
Mussaenda erythrophylla Schum. & Thonn. Dona Trining (Tag.)
Mussaenda fulgens R. Br. ex Tedlie Ashanti blood (Engl.)
Mussaenda splendida Welw. Red flag bush (Engl.)
  Red mussaenda (Engl.)
  Tropical dogbush (Engl.)

Botany
Mussaenda erythrophylla is a perennial, evergreen shrub with a branched tap root system. Flowers are big, creamy-white or yellow, orange, with reddish rings at the center. Leafy sepals are ovate, up to 9 centimeters long, rich vermillon-scarlet, with lighter colored veins.

Distribution
- Introduced to the Philippines, probably after the Second World War.
-
Cultivated in gardens in the Philippines.
- Cultivated as ornamental plant in India.
- Native to western tropical Africa.


Constituents
- Study of stems yielded β-sitosterol, 5 hydroxy-7, 4'-dimethoxy flavones, 3- iso cumaryloxy – cyclopropane-1-oic acid and 4 -hydroxy-3-methoxy cinnamic acid.
- Phytochemical screening
yielded phytosterols, triterpenes, and flavonoids.
- Studies have previously isolated triterpenoids and glycosides, mussaendosides A-C, M and N with clyclolanostene type aglycone and aureusidin, iridoid glycosides.


Uses

Folkloric
- No reported folkloric medicinal use in the Philippines.
- Elsewhere, reported use for cough, jaundice, and when chewed, as appetizer.


Studies
Anthelmintic:
Extracts from A. leptopus roots and rhizomes and Mussaenda erythrophylla roots were tested for in vitro anthelmintic activity against earthworm Pheretima posthuma. Both plants showed potent activity. The ethyl acetate extract of M. erythrophylla was more potent than the methanol extract.
Hepatoprotective: Study of ethyl acetate and methanol extracts of stems of ME against CCl4-induced liver damage in Wistar albino rats showed hepatoprotective effects with significant reduction of hepatic enzymes and reduction in pathologic changes (centrilobular necrosis and
vacuolization).

Availability
Wild-crafted.

January 2012

IMAGE SOURCE: English: Mussaenda erythrophylla / File:Mussaenda erythrophylla02.JPG / 20 December 2009 / Meneerke Bloem / GNU Free Documentation / Wikipedia
OTHER IMAGE SOURCE: English: Mussaenda erythrophylla / File:Mussaenda3.jpg / El Denis Conrado, en la urbo Lavras, MG., Brazilo. / GNU Free Documentation / Wikipedia

Additional Sources and Suggested Readings
(1)
ANTHELMINTIC ACTIVITIES OF ANTIGONON LEPTOPUS HOOK AND MUSSAENDA ERYTHROPHYLLA LAM / N. JAYA RAJU, B. GANGA RAO / International Journal of Pharmacy and Pharmaceutical Sciences, Vol 3, Issue 1, 2011
(2)
HEPATOPROTECTIVE ACTIVITY OF EXTRACTS FROM STEM OF MUSSAENDA ERYTHROPHYLLA LAM. AGAINST CARBON TETRACHLORIDE - INDUECD TOXICITY IN RATS / M Chinna Eswaraiah, T Satyanarayana / Asian JPRHC, January 2010, Vol 2, No 1
(3)
Isolation of phytoconstituents from the stems of Mussaenda erythrophylla / M. Chinna Eswaraiah* and A. Elumalai / Pelagia Research Library Der Pharmacia Sinica, 2011, 2 (6):132-142


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