Family Polygonaceae
Sea grape
Coccoloba uvifera Linn.

Common names
Sea grape (Engl.)
Uva de playa (Span.)
Platter leaf (Engl.)



Botany
A sprawling bush or small tree, growing to a maximum height of 8 m. Bark is smooth and yellowish.Leaves are alternate, short-petioled, large, leathery, glossy, dark green, broadly bean-shaped, with wavy margins, up to 15 cm long, with a reddish-colored primary vein extending from the base. Flowers are small, white and fragrant in terminal racemes, with five petals and eight stamens. Fruits are pear-shaped, reddish purple and green-dotted, 1.5 cm long, clustered in pendulous branches.

Distribution
Salt tolerant, planted near beaches edges.
Ornamental distribution in parks and gardnes.
Propagated by seeds, layering, or stem cuttings.

Parts utilized
Leaves, bark, foots, fruit.

Uses
Folkloric
No reported folkloric medicinal use in the Philippiines.
In other countries, juice and decoction of wood, bark and roots are used to treat dysentery, hemorrhages, venereal disease.
Applied externally for rashes and skin afflictions.
Decoction of leaves used to treat asthma, hoarseness and to wash wounds.
Others
Fruit is edible, eaten off the tree or made into jams, jellies and wine.
Resin of the bark used for tanning and dyeing.
Wood is used for fuel and making furniture.

Studies
Phytochemical: Studies show the chemical composition of Coccoloba uvifera as: Alpha-Amyrin (antitumor, cytotoxic), chrysophanol (antiseptic, bactericial, cathartic, hemostat, purgative), emodin (anti-aggregant, antiinflammatory, antitumore, antiulcer, immunosuppressive, viricide), physcion (antiseptic, cathartic, purgative), rhein, anticarcinomic, antitumore, fungicide), royleanone, beta-sitosterol (hypoglycemic, hypolipidemic, hypocholesterolemic, hepatoprotective).
Glucose Lowering: Case studies have shown glucose lowering effect with daily ingestion of tea brewed from Coccoloba uvifera leaves. There is concern for lowering the blood sugar too much, especially with concurrent use of pharmaceutical hypoglycemics.
Preparation of Leaf Extract: Preparationn of leaf extract is done by immersing coccoloba uvifera leaves in water, heating the water to boiling for about 4 hours. This brewing time must be just enough to dissolve the compound from the leaves. The active compounds are resistant to the low gastric pH and high temperatures.
• The preferred embodiment is a ratio of 4 green leaves to every 3.8 liters of water.
• Alternatively, leaf extract can be done by drying the c. uvifera leaves and dehydrating the pulp into a tea. In a preferred embodiment, 15 cc of the tea is dissolved in 3.8 liters of water before ingestion.
• Other forms of delivery may be through tablets, capsules, powders, seasoning.
• A distinct advantage of the leaf extract is its oral route and its resistance to the digestive processes of the stomach. source
Photoprotective / Antioxidant: Coccoloba uvifera showed antioxidant and anti-tyrosinase activities, and also inhibited the production of interleukin-1a and TNF-a and a-MSH in melanocytes subjected to UV radiation.

Antibacterial / Antifungal / Phytochemicals: Study yielded flavonoids, saponins, polyphenols and tannins. Ethanolic and methanol extracts inhibited the growth of E coli and P aeruginosa and showed antifungal activity against C albicans, Fusarium oxysporum and F. decencellulare.

Availability
Wildcrafted.



Additional Sources and Suggested Readings
(1)
Cesiak
(2)
Method of controlling blood sugar levels using Coccoloba uvifer / Patent Storm
(3)
Effects of Coccoloba uvifera L. on UV-stimulated melanocytes / Jessica Eleonora Pedroso Sanches Silveira et al / Photodermatology, Photoimmunology & Photomedicine. Volume 24 Issue 6, Pages 308 - 313 / 10.1111/j.1600-0781.2008.00382.x About DOI
(4)
Three constituents with biological activity from Coccoloba uvifera seeds / Shailili Moreno Morales et al / Ciencia vol.16 no.1 Maracaibo Mar. 2008


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