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Botany
A liana, ie, a woody,
perennial, climbing plant with a very long stem growing from the ground
level to the canopy of trees. The stems are about 5 cm thick, with a
gray bark and yellow wood. Leaves aresimple and alternate, leathery,
smooth, and broadly ovate, , 16 cm wide and 16 cm long, the tip abruptly
pointed, the base obtusely round or subtruncate, with 5 veins radiating
from the base, with one or two lateral nerves in the midvein. Inflorescence
isaxillary, pendulous and spicately panicled, clustered along the stems.
Flowers are fragrant, yellowish, crowded and stalkless.
Distribution
In thickets and
forests, at low and medium altitudes.
Constituents
and chemical properties
Stems yield a yellow
dye, berberine.
The plant yields several alkaloids: berberine, jatrorhizine, columbamine
nad shobakunine.
Antimalarial.
Germicide.
Tonic.
Stomachic, febrifuge, emmenagogue, abortive, antiperiodic, diaphoretic
(much of these due to the berberine).
Parts
used and preparation
Bark, roots, and
stems.
Uses
Folkloric
• Itching and tropical
ulcers: Apply decoction of plant on the affected area.
• Decoction of wood used to clean wounds.
• Decoction of roots and stem used as febrifuge, tonic. Also used
as abortive.
• Used as expectorant.
• In East Asian traditional medicine, used as bitter tonic and
for jaundice, infectious diarrheal disease and skin abscess.
Others
Stems used for its yellow
dye (berberine), a single plant yielding as much as one kilo of berberine.
Studies
• Antioxidant
/ Cytotoxic: Antioxidant
and cytotoxic activities of A. flava, C. blumeanum and F. tinctoria:
A study showed alkaloids extracts showed of A. flava showed antioxidant
activity and pronounced cytotoxic activity against human cancer cell
line MCF-7 (breast adenocarcibnoma). Berberine, palmatine and jatrorrhizine
were isolated from A. flava.
• Antimalarial / Cytotoxic: Antimalarial
and cytotoxic activities of ethnopharmacologically selected medicinal
plants from South Vietnam: A study showed Arcangelisia
flava as one of 49 plants showing antiplasmodial activity.
• Phytochemical Study: Study
yielded four new furanoditerpenes plus fibraurin, fibleucin, and 6-hydroxyfibraurin.
• Antibabesial Activirty: Study
isolated palmatine, berberine, jatrorrhizine, dihydroberberine and 20-hydroxyecdysone.
Four compounds caused significant inhibition of Babesia gibsoni, an
intraerythrocytic parasite that causes hemolytic anemia in wild and
domesticated dogs. The mechanism was possibly through prevention of
parasite invasion of erythrocytes and inhibition of growth.
• Genotoxicity: In a study of 138 medicinal plant preparations used in the Philippines
were studied for genotoxicity. 12, including A. flava exhibited detectable
genotoxicity.
Availability
Wild-crafted. |
