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Anjenjo
Crossostephium chinense Linn.
CHINESE WORMWOOD

Other scientific names  Common names 
Artemisia chinenses Linn. Anjenjo (Tag.)
Tanacetum chinense A. Gray Anghingho (Tag.)
Chrysanthemum artemisioides Kitam. Fu jung (Taiwan)

Botany
A low, erect and branching perennial, growing to 50 cm. Leaves are dissected, narrow gray-green on a woody stem.

Distribution
Native to China.
Probably introduced to the Philippines in the early Spanish times.
Ornamental cultivation.

Parts used
Leaves and stems.

Uses
Folkloric
Not well known for its folkloric medicinal use.
In the some parts of rural Quezon, used for hepatitis and arthritis.
In Taiwan, a folkloric medicine for common colds, rheumatoid arthritis..
In China, leaves and stems used in making moxa.

Availability
Antioxidant / Antiproliferative: Both water and methanol extract showed ability to dose-dependently scavenge free radicals. The water extract showed higher antioxidant and antiproliferative activities than the methanol extract.Study showed the water extract of Crossostephium chinensis might be used as a potential source of natural antioxidants and as anti-tumor agent.
Chemical Constituents: Study isolated eight compounds from the whole plant of C chinense: taraxerol, alpha-amyrin acetate, beta-amyrin acetate, beta-sitosterol, 3-beta-acetoxy-12ursen-11-one, uracil and 5-O-methyl-myo-inositol. Six were isolated for the first time.
Insulin Secretion Effects: Chemical constituents isolated from the whole herb were tested on its effects on insulin secretion in rat islets. Quercetagetin-3,6,7-trimethylether and 5-O-methyl-myo-inositol showed to enhance rat islet insulin secretion while scopletin suppressed rat islet insulin secretion.
Sesquiterpenes / Coumarins: Study of ethanolic extract yielded crossostephin and coumarin, biscopoletin, with four other known compounds, artesin, tanacetin, scopoletin and scopolin.

Availability
Wild-crafted

Additional Sources and Suggested Readings
(1)
Antioxidant and Antiproliferative Activities of Crossostephium chinensis (L.) Makino
/ Tien-Ning Chang et al / American Journal of Chinese Medicine, Vol 37, No 4, pp 797-814
(2)

Studies on chemical constituents from whole plants of Crossostephium chinense / Yang X W et al / Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(8):905-8.
(3)
Effects of chemical constituents of Crossostephium chinense on insulin secretion in rat islets in vitro / Zou L et al /Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(11):1401-5
(4)
Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense / Qi Wu et al / Journal of Asian Natural Products Research, Volume 11, Issue 1 January 2009 , pages 85 - 90 / DOI: 10.1080/10286020802435703


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