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Apatot
Noni
Morinda citrifolia
INDIAN MULBERRY

Other scientific names  Common names   
Morinda littoralis  Apatot (Ilk.)  Lino (Bis., Tag.)
  Apatot-nga-basit (Ilk.)  Nino (Sul., Tag., Bis.) 
  Bangkudo (Bis., Tag.)  Rukurok (Kuy.) 
  Bankoro (Tag., Mag.)  Tueng-aso (Tag.) 
  Bankuro (Tagb.)  Tumbong-aso (Tag.) 
  Bankuru (Tag.) Indian mulberry (Engl.) 
  Galongog (Sub.)  Tahitian noni (Engl.) 

Botany
Erect, smooth shrub or small tree, 4-10 meters high. Leaves are broadly elliptic to oblong, 12-25 cm long, with pointed or blunted tips. Peduncles are leaf-opposed, solitary, 1-3 cm long. Flowers are dense, ovoid; calyx is truncate. Corolla is white, 1 cm long; limb is 5-lobed, 1 cm in diameter. Fruit has the odor of decaying chees; is fleshy, white or greenish white, ovoid, 3-10 cm long.

Distribution
Along or near seashores, throughout the Philippines.

Parts utilized
:
Roots, bark, leaves.

Properties
Fruit is emmenagogue.
Root is cathartic.
Bark, because of morindine, is febrifuge
Tonic
Fruit contains phytochemicals: lignans, polysaccharides, flavonoids, iridoids, nonisides, scopoletin, catechin and epicatechin, damnacanthal, alkaloids.

Uses
Edible
Fruit is edible, but not great tasting, raw or cooked, salted or curried.
Fruit occasionally used as pig feed.

Folkloric
Fruit is used as emmenagogue.
Leaves, when fresh, applied to ulcers, facilitates healing.
Heated leave applied to the chest for coughs, nausea, colic, fever.
Decoction of charred leaves with mustard for infantile diarrhea.
Juice of over-ripe fruit used for diabetes.
Juice of fruit pulp, mashed with sugar, is slightly laxative.
Syrup of fruit juice used as a gargle for sore throats.
Leaves, fruit, flowers or bark used for eye problems, wounds, abscesses, fever, constipation.
Leaf juice used for arthritis.
In Polynesian traditional medicine, used for anticancer activity.
Others
Pulp of fruit used for cleaning hair, iron, or steel.
Young leaves may be eaten as vegetable.
Tonic drink is prepared from decoction of pounded leaves and stem bark.
Bark produces a reddish purple to brown dye used in batik making.
Noni rage
Briefly ruled as a herbal dietary supplement snake oil cure-all (Noni Juice or as a morinda capsule supplement ) claiming a wide range of therapeutic effects: antibacterial, antiviral, antifungal, antitumor, analgesic, hypotensive, anti-inflammatory, and immune enhancing effects among many others.

Studies
Antioxidant / Anticancer: Study suggest the prevention of carcinogen-DNA adduct formation and the antioxidant activity from commercial juice made from M citrifolia fruit may contribute to the cancer preventive effect of M citrifolia.
Nitric Oxide Scavenging Activity: Study of plant extracts of 17 Indian medicinal plants, M citrifolia was third in potency of dose-dependent nitric-oxide scavenging activity.
Herbal Hepatotoxicity / Case Report: Report of a case of hepatotoxicity from a three-week history of drinking Noni juice. Pathology was confirmed by liverf biopsy. Transaminase levels normalized within a month.
Antispasmodic / Vasodilator Activities: Results suggest the spasmolytic and vasodilator effects of Moringa citrifolia are mediated possibly through blockade of voltage-dependent calcium channels and release of intracellular calcium – mechanisms that may explain its use in diarrhea and hypertension.
Analgesic: Study suggests the alcoholic extract of fruits of Moringa citrifolia appears to have an analgesic effect. Morphine sulfate was the reference drug.
Wound Healing / Antioxidant: Study showed antioxidant and wound healing activities: increase in wound contraction rate, tensile strength, granuloma breaking strength, collagen content and hydroxyproling content.
Antiviral / Cytotoxicity: Study of fruit juice of M citrifolia displayed marked cytotoxicity in lymphocyte (MT-4) cells and inhibition of HCV subgenomic replicon replication in Huh 5-2 cells.
Apoptosis-Inducing Effects/ Cytotoxicity: Results showed an anti-growth effect from induction of apoptosis. Study showed noni may be useful in the treatment of breast cancer either on its own or in combination with doxorubicin.


Availability
Wild-crafted.



Additional Sources and Suggested Readings
(1)
Cancer Preventive Effect of Morinda citrifolia (Noni)
/ M Y Wang and C Su /
(2)
The Evaluation of Nitric Oxide Scavenging Activity of Certain Indian Medicinal Plants In Vitro: A Preliminary Study / Ganesh Chandra Jagetia et al / Journal of Medicinal Food. Fall 2004, 7(3): 343-348. doi:10.1089/jmf.2004.7.343.
(3)
Great Morinda • Morinda citrifolia / Ria Tan, 2001
(4)
Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia) / Millonig Gunda et al / European Journal of Gastroenterology & Hepatology: • April 2005 - Volume 17 - Issue 4 - pp 445-447
(5)
Noni / Wikipedia
(6)
HEALTH BENEFITS OF MORINDA CITRIFOLIA: TAHITIAN NONI JUICE / Harrison Mona MD /
(7)
Antispasmodic and vasodilator activities of Morinda citrifolia root extract are mediated through blockade of voltage dependent calcium channels / Anwarul Hassan Gilani et al /
BMC Complementary and Alternative Medicine 2010, 10:2doi:10.1186/1472-6882-10-2
(8)
ANALGESIC EFFECT OF THE ALCOHOLIC EXTRACT FROM THE FRUITS OF MORINDA CITRIFOLIA / T Punjanon and P Nandhasri / URL www.actahort.org
(9)
Wound Healing and Antioxidant Activities of Morinda citrifolia Leaf Extract in Rats / Vijaykumar Pandurang Rasal et al / Iranian Journal of Pharm and Therapeutics | January 2008 | vol. 7 | no. 1 | 49-52
(10)
Studies of antiviral activity and cytotoxicity of Wrightia tinctoria and Morinda citrifolia / P selvam et al / Indian J Pharm Sci 2009;71:670-2 / DOI: 10.4103/0250-474X.59550
(11)
Apoptosis-inducing effects of Morinda citrifolia L. and doxorubicin on the Ehrlich ascites tumor in Balb-c mice / Elif lkay Takn et al / Cell Biochemistry and Function • Volume 27 Issue 8, Pages 542 - 546


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