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Family Lamiaceae
Mayana
Plectranthus scutellarioides (L.) R. Br. 

PAINTED NETTLE
Wu cai su

Scientific names Common names
Calchas acuminatus (Benth.) P.V.Heath Badiara (Tag., Bis., Pamp.)
Calchas atropurpureus (Benth.) P.V.Heath Dafronaya (Span.) 
Calchas crispipilus (Merr.) P.V.Heath Daponaya (Bis.) 
Calchas scutellarioides (L.) P.V.Heath Lapunaya (Bis.) 
Coleus acuminatus Benth. Malaina (Tag., Bis., Pamp.) 
Coleus atropurpureus Benth. Marayapa (Pamp.)
Coleus blancoi Benth. Mayana (Tag., Bis., Pamp.)
Coleus blumei Benth. Saimayu (Sul.) 
Coleus crispipilus (Merr.) Merr. Taponaya (Bis.) 
Coleus formosanus Hayata Tapunaya (Bis.) 
Coleus gaudichaudii Briq Butterfly coleus (Engl.)
Coleus gibbsiae S.Moore Coleus (Engl.)
Coleus grandifolius Benth. Common coleus (Engl.)
Coleus hybridus Cobeau Flame nettle (Engl.)
Coleus igolotorum Briq. Joseph's coat (Engl.)
Coleus ingratus (Blume) Benth. Painted nettle (Engl.) 
Coleus integrifolius Elmer  
Coleus lanciniaatus (Blume) Benth.  
Coleus multiflorus Benth  
Coleus pubescens Merr.  
Coleus pumilus Blanco  
Coleus rehneltianus A.Berger  
Coleus savannicola K.Schum.  
Coleus scutellarioides (L.) Benth.  
Coleus secundiflorus Benth.  
Coleus verschaffeltii Lem.  
Coleus zschokkei Merr.  
Germanea nudiflora Poir.  
Majana acuminata (Benth.) Kuntze  
Majana blancoi (Benth.) Kuntze  
Majana grandiflora (Benth.) Kuntze  
Majana multiflora (Benth.) Kuntze  
Majana pumila (Benth.) Kuntze  
Majana scutellarioides (L.) Kuntze  
Majana secundiflora (Benth.) Kuntze  
Ocimum peltatum Schweigg. ex Schrank  
Ocimum scutellarioides L  
Perilla nankinensis Wender.  
Plectranthus aromaticus Roxb.  
Plectranthus blumei (Benth.) Launert  
Plectranthus ingratus Blume  
Plectranthus laciniatus Blume  
Plectranthus nudiflorus (Poir.) Willd.  
Plectranthus scutellarioides (L.) R.Br.  
Solenostemon blumei (Benth.) M.Gomez  
Solenostemon scutellarioides (L.) Codd  
Mayana is a shared common name of (1) Coleus atropurpureus, badiara, and (2) Coleus blumei. Some compilattions list the two species as synonymous.
Quisumbing's compilation lists Coleus blumei (Mayana) as synonym of Plectranthus scutellarioides Blume.
The name "coleus", still widely used by horticulturists and gardeners, is considered a defunct genus. Species have been placed under genus Solenostemon and genus Plectranthus. Wikipedia
Coleus atropurpureus Benth. is a synonym of Plectranthus scutellarioides (L.) R.Br. The Plant List
Plectranthus scutellarioides (L.) R.Br. is an accepted name. The Plant List

Other vernacular names
CHINESE: Wu cai su.
FIJIAN: Lata.
GERMAN: Buntblatt, Buntnessel.
INDONESIA: Daun iler, Miana, Ati-ati, Jawer kotok.
SPANISH: Ahijado, Nene.
SWEDISH: Palettblad.

Compilations and studies suggest that Plectranthus scutellarioides and Coleus blumei are synonyms. The two plant pages on Badiara and Mayana are being merged. (G, Stuart)

Gen info
- Taxonomy: Quisumbing's compilation lists Coleus atropurpureus (badiara) and Coleus blumei as separate species. More recent compilations list the species as synonymous. K. Heyne does not separate it from C. blumei (now Solenostemon scutellarioides). (11) The name 'Coleus', widely used by horticulturists and gardeners, refers to a defunct genus. The species has been placed under genus Solenostemon and genus Plectranthus. (22)
- Etymology: The genus name Sollenostemon is derived from the Greek words 'solen' meaning tube and 'stemon' meaning stamen. The specific epithet scutellarioides means 'resembling scutellarioides.' In Latin, scutella means a small dish or bowl.
(22)
- There are more than 173 varieties of P. scutellarioides all over the world.
- Ornamental cultivation for its decorative variegated leaves, Varieties include Aurora, Religious Radish, Red Trailing Queen, Trailing Bleeding Heart, Trailing Salamander, Ruby Ruffles, Vulcan, and Meandering Linda.
- There was a report of psychoactive use among the Mexican Mazatecs discovered in 1962 in connection with Gordon Wasson's research into Salvia divinorum.
- There is a large number of Coleus blumei hybrids which can be mistaken for other Coleus species.

Botany
Mayana is an erect, branched, fleshy, annual herb, about 1 meter high. Stems are purplish and 4-angled. Leaves are variously blotched or colored, usually more or less hairy, ovate, 5 to 10 centimeters long, rather coarsely toothed in the margins; and in the most common form uniformly velvety-purple. Flowers are purplish, numerous, and borne in lax, terminal, simple or branched inflorescences, 15 to 30 centimeters long. Calyx is green, and about 2.5 millimeters long, with the upper lip ovate and the lateral lobes short and ovate, the lower one being 2-cleft. Corolla is about 11 millimeters long.

Distribution
- Introduced in the Philippines.
- Cultivated for ornamental purposes.

- Popular for its incredible range of foliage colors.
- Native of Java.
- Now, a pantropic ornamental.
- Various species of Solenostemon scutellarioides include Aurora. Religious Radish, Red Trailing Queen, Trailing bleeding heart, Trailing Salamander, Ruby Ruffles, Vulcan, and Meandering Linda.

Constituents
- Volatile oils.
- Leaves reported to yield psychoactive material.
- From the leaves, study isolated a mixture of sterols and triterpenes, campesterol, α-amyrin and ß-amyrin.
- Yields salvinorinlike substances
of undetermined chemical structures.
- Screening yielded flavonoids, sterol and triterpenoid compounds.
- Leaves have yielded alkaloids, saponin, flavonoids, tannin, volatile oils, and quercetin. (13)
- Phytochemical screening of crude leaf extract yielded terpenoids, phenolic compounds, saponins, and anthraquinones. (see study below) (19)
- TLC and GC-MS study of leaves yielded essential oil content of 0.04% v/w. Organoleptic properties were the form of brownish yellow liquid, taste of sponge, and smell of tea. Main constituents were phytol 21.1%, germacrene-d 9.30%, caryophyllene 8.84%, ß-elemene 6.84%. and neophytadiene 6.08%. (27)
- Study of aerial parts yielded three new compounds, diterpenoid glucoside (13S,15S)-6ß,7a,12a-trihydroxy-13ß,16-cyclo-8-abietene-11,14-dione 7-O-ß-D-glucoside (1), flavonoids apigenin 7-O-(3"-O-acetyl)-ß-D-glucuronide (2) and apigenin 5-O-)3"-O-acetyl)-ß-D-glucuronide (3), together with known compounds caffeic acid (4), luteolin 5-O-ß-D-glucoside (5), and rosmarinic acid (6). (see study below)    (28)
Study of leaves isolated three new diterpenoids, spirocutelones A-C (1-3), along with known diterpene (4). (see study below) (29)

Properties
- Carminative, vulnerary.
- Studies suggest antimicrobial, antioxidant, anthelmintic, antimalarial, analgesic, anti-inflammatory, immunostimulant, wound healing, larvicidal, phytoremediative, COX inhibitory, anticancer, antidiabetic, butyrylcholinesterase inhibitory, fungistatic properties.

Parts used
Leaves, seeds, bark.

Uses
Folkloric
• In the Philippines, pounded leaves used as a cure for headaches, applied to the temples or nape of the neck. Also used for healing bruises.
• Used by the Ati tribe in Malay, Aklan for fever and headaches. (
36)
• Decoction taken internally for dyspepsia and for wasting away.
• Decoction used as eye drops for ophthalmia and conjunctivitis.
• For bruises and sprains, 10-12 leaves are crushed or pounded and applied over the ankles, wrists or affected areas for 30 minutes, three times daily, the poultice held in place by a bandage.
• Carminative: Take decoctions of leaves.
• Mild bleeding of wounds: Wash the young leaves; crush and extract the juice. Drop a few drops of the juice directly on the wound. Apply the crushed leaves as poultice.
• Sinusitis: Heat 10-12 fresh leaves over a fire; apply while still hot over the forehead for the frontal sinuses or over the cheeks for the maxillary sinuses, twice daily.
• Dyspepsia: Decoction, taken internally.
• Reported use in Asian traditional medicine for asthma, angina, bronchitis, epilepsy, insomnia, skin rashes and various digestive problems.
In India, fresh juice of leaf and stem is mixed with the juice of raw Citrus fruits and applied over the skin during scorpion bite.
source
In Samoa, used to treat elephantiasis.
In Southeast Asia, used to treat dysentery and various digestive problems.

In Vanuatu, leaves used for abortion; also for amenorrhea. Sap is used as contraceptive, and whole plant leaves used as emmenagogue. Leaves also used to facilitate lactation by heating or softening flowers in hot water and applying the preparation on the nipples. (14)
• In Fiji, used to treat diarrhea; juice of leaves used to treat earache.
- From Thailand to Malaya, pulped leafy stems or decoction used to stimulate digestion, used to relieve pain ascribed to the heart, congestion of the liver with swollen hands and feet. Leaf paste sometimes applied over the stomach, heart and glandular swellings.
- Elsewhere, decoction used internally for dyspepsia and wasting.
- Used as drops for ophthalmic.
- Also used for hemorrhoids and to regulate menstruation.
- Once used to prevent conception.
- Roots used for colic and diarrhea.

- In Indonesia, the color blaze dark star variety, known as miana or iler, is used fresh, boiled, or infused to treat blain, abscesses, ulcers, eye and ear inflammation. Roots used for diarrhea and stomach pains; also for diabetes, constipation, fever, and dysmenorrhea. Ethnic Toraja use miana leaves to treat pulmonary tuberculosis. (43)
Others
Psychoactive: The psychoactivity of the leaves is highly controversial. (1) There are reports of psychoactive effects from the smoking of leaves. Leaves are dried and soaked alone or mixed with other herbs, and the psychoactive effect achieved with as few as 3 leaves. (2) The Mazatecs consider coleus as a member of the "family" of psychoactive herbs, using coleus as a substitute for Salvia divinorum. (3) About 30% of subjects who smoked dried Mexican Coleus blumei leaves reported effects similar to smoking a small dosage of Salvia divinorum. (4) Some experience no effects with large amounts of leaves.
• Dye:
Sap from leaves of the wild, purple-black species used in tattooing. (18)
• Toxicity:
Reported toxicity to dogs from ingestion of leaves.

Studies
Antimicrobial / Diterpenes:
Diastereomeric Diterpenes from Coleus blume: Study yielded a new abietane type diterpene that showed antimicrobial activity against B subtilis, P aeruginosa and C albicans. (1)
Antioxidant:
Antioxidant Activity of Coleus Blumei, Orthosiphon Stamineus, Ocimum basilicum and Mentha arvensis from Lamiaceae Family: Study showed all methanol samples exhibited antioxidant activity and suggested that Lamiaceae plants has pharmaceutical potential for its antioxidant properties. (2)
Forskolin / Erectile Dysfunction:
Study has shown forskolin may enhance smooth muscle relaxation. Studies are needed to assess the use of coleus in the treatment of erectile dysfunction.
Anthelmintic:
Leaf extract showed high efficacy against Hymenolepsis nana (mice). (4)
Analgesic / Anti-Inflammatory / Antimicrobial:
Study isolated a mixture of sterols and triterpenes from the leaves of Coleus blumei. The isolates exhibited analgesic, anti-inflammatory and antimicrobial activities. The study also isolated campesterol, α-amyrin and ß-amyrin. (5)
Antioxidant / Phenolic Content / Minerals:
Study investigated whether antioxidant, minerals and phenolic content can be extracted by boiling the leaves in water. The mineral concentration, antioxidant activity and phenolic content seemed to be highly correlated. Study concludes the leaves have a high potential value for a nutritional purpose. (9)
Antibacterial / Antitumor:
An ethyl ethanoate soluble separate of an ethanol extract showed antibacterial and anti-tumor properties.
Quercetin / Histamine H4 Receptor Inhibitor:
A Plecranthus leaves extract yielded 0.05% quercetin. Quercetin is known to have a strong affinity for mast cells and basophils. The compound was able to interact with H4R. Results suggest Plecranthus leaves extract might have potential use as histamine H4 receptor inhibitor.
(13)
Phytoremediation with Selenium Treatment / Lead Exposure:
Study showed lead (Pb) is tolerated by coleus plants through allocation plasticity, activation of antioxidant systems, and improvements in particle size and mineralogical effects. C. blumei can be useful in phytoremediation of aquatic systems contaminated with Pb, especially with addition of low concentrations of selenium.
(15)
Anti-Malarial:
Study investigated the in-vivo antiplasmodial activity of a combination of Piper betle fruit, Plectranthus scutellarioides, honey and egg yolk inoculated into Swiss albino mice infected intraperitoneally. Results showed inhibition of Plasmodium berghei parasitemia, suggesting a possible therapeutic value in human malaria, and suggesting further investigation in different experimental models. (16)
• Larvicidal / Leaves:
Study for larvicidal activity of leaf extract against 2nd and 3rd instar larvae of Aedes aegypti showed high mortality with 96.11 ± 1.389% and LC50 of5.85 ± 0.4719 ppm. Potential as insecticide against A. aegypti was attributed to phytol and other essential oils such as sesquiterpenes and diterpenes. (see constituents above) (19)
• Wound Healing / Leaf Ointment:
Study evaluated ointment formulation from air dried leaves for wound healing activity on inflicted wounds on albino rats. Results showed significant wound healing activity with a significant decrease in wound length and size. Phytochemical screening yielded polyphenols, flavonoids, saponins, and quinones. (20)
• Inhibition of COX Enzymes:
Study evaluated the pharmacologic activity of P. scutellarioides leaf extracts on cyclooxygenases (COX) and xanthine oxidase (XO) enzymes. Results showed COX-1 inhibition of 40.43% and COX-2 at 97.04%. All the leaf extracts showed inhibitory activity on XO enzyme, possibly attributed to the presence of benzopyran ring in the flavonoids. Results suggest potential as XO and nonselective COX inhibitors. (21)
• Fungistatic / Effect on Expression of mRNA IL-37 in Mice Infected with Candida albicans / Leaves:
Study analyzed IL-37 expression following administration of miana leaf extract (MLE) in an animal model of vulvovaginal candidiasis. Results suggest a component within the MLE may mediate its anti-inflammatory characteristics as indicated by an increase in mRNA IL-37 expression in mice inoculated with C. albicans. The fungistatic effect of MLE is not less than ketoconazole and may act as an anti-inflammatory through its antioxidant effect. Study suggests an alternative treatment for patients with vulvovaginal candidiasis. (23)
• Effect of Tissues on Romarinic Production: Rosmarinic acid is one of the main components of C. blumei which is known to have numerous health benefits. Study evaluated the ability of different tissues to accumulate rosmarinic acid and sustainability in production over long cultivation. Hairy root lines showed the highest mean growth rate and consistency in rosmarinic production. Dichlorophenoxyacetic acid (DAA) significantly reduced tumor growth and rosmarinic production. 1-Naphthaleneacetic acid strongly stimulate hair root growth while abscisic acid strongly enhanced rosmarinic production. Hairy roots cultured in an airlift bioreactor showed the highest potential for mass production of rosmarinic acid. (24)
Antioxidant / Butyrylcholinesterase Inhibitory Activity / Aerial Parts: Study of aerial parts isolated and identified six compounds from P. scutellarioides. Abietane glucoside and flavonoid glucuronides were isolated for the first time. The flavonoids inhibited butyrylcholinesterase better than galanthamine. Abietane glucoside and rosmarinic acid suppressed hyaluronidase. Rosmarinic acid showed the highest antioxidant activity. (see constituents above) (28)
Cytoxicity Against Cancer Cell Lines / Abietane-Type Diterpenoids / Leaves: Study of leaves isolated three new diterpenoids, spirocutelones A-C (1-3), along with known diterpene (4). Compound 2, spiroscutelone B exhibited the most potent cytotoxicities against three tested cancer cell lines: breast (MCF-7), pancreatic (PSN-1), and cervical (HeLa) with IC50s ranging from 17.9 µM to 29.8 µM and low cytotoxicity against a lung fibroblast (WI-38) normal cell line. (29)
Antidiabetic Activity / Leaves: Study evaluated an ethanol extract of iler leaves for bioactive compounds and antidiabetic activity in white male Swiss Webster mice induced by alloxan. Glibenclamide was used as positive control. An ethyl acetate fraction (Ps-II) showed significant reduction in blood glucose level (37.65%). Further subfractions of ethyl acetate fraction showed significant antidiabetic activity (p<0.05) with 30.64% to 44.82% range of decrease of blood glucose levels. (30)
Antipyretic: Study evaluated the antipyretic activity of P. scutellarioides extract of Swiss Webster male mice with pyrexia induced by diphtheria-pertusis-tetanus (DPT) vaccine. Results showed reduction in body temperature by 80.47% at 280 mg/kbw compared to paracetamol 85.43% at 130 mg/kbw. Of interest, higher extract dose decrease the antipyretic effect. (31)
Anti-Inflammatory / Antiproliferative / Diterpenoids / Aerial Parts: Study of dichlormethane extract of aerial parts isolated 10 diterpenoids. The isolated constituents were evaluated for in vitro NF-kB inhibitory activity and cytotoxic effects in human multiple myeloma cancer stem cells and RPMI 8226 tumor cell line. Coleon O, coleon G, lanugone K and 6-acetylfredericone B showed highest inhibitory activity against NF-kB, with IC50s of 11.2, 11.0, 4.5, and 9.7 µM, respectively. Coleon O also showed significant activity towards human multiple myeloma cancer stem cells and RPMI 8226 cells with IC50s of 9.2 and 8.4 µM, respectively. (32)
IgM Antibody Response on Systemic Candidiasis / Leaves: Study evaluated the colony fungi loads, IgM antibody responses, and correlation in Balb/c mice infected with C. albicans treated with oral ethanol leaf extract of PS. Results showed ingestion of ELEP significantly affected fungal load clearance and decreases IgM antibody levels compared to the control group (p<0.001). Ingestion of ELEP was associated with lower concentration of IgM antibodies and colony forming units (p<0.001). Results strongly suggest the IgM antibody response is involved in the mechanism by which ELEP decreases C. albicans infection. (33)
Effect of Leaf Temperature and Blue Light on Rosmarinic Acid: Study evaluated the influence of different lamp types on physiology and secondary metabolites of P. scutellarioides. Results showed stem elongation was increased in PS by increased FR light. Higher infrared radiation resulted in faster plant development. Content of rosmarinic acid and phenolic compounds were mainly influenced by leaf temperature. Blue light increased leaf thickness and led to a higher accumulation of RA per leaf area.   (34)
Green Extraction of trans Rosmarinic Acid / Leaves: Painted nettle (P. scutellarioides) leaves is one of the richest sources of trans-rosmarinic acid, an antioxidant and antimicrobial phenolic compound. Study reports on the optimization and validation of an ultrasound-assisted extraction method. Highest content was obtained using pure ethanol as extraction solvent. The antioxidant (in vitro radical scavenging) and antimicrobial (S. aureus) activities were significantly correlated with trans rosmarinic acid concentration. (35)
Antibacterial / Leaf Essential Oil: Study profiled the leaf essential oil and antibacterial activity of P. scutellarioides. Hydrodistillation yielded 0.18% essential oil, and GC-MS study yielded 28 constituents, with an abundance of spathulenol (24.57%), D-germacrene (14.53%), bicyclogermacrene (11.24%), nonacosane (9.74%), and morillol (4.85%). Antibacterial evaluation of the EO showed activity against all test strains of 8 different gram negative and positive bacteria. Strongest activity was against multidrug resistant strains of E. coli (MIC 0.625 mg/mL) and methicillin resistant S. aureus *2.5 mg/mL). (37)
Activation of Anti-Tuberculous Drug Rifampicin: Study evaluated the anti-mycobacterial bioactivity of non polar compounds from Coleus atropurpureus. A cyclic ester terpenoid, 2', 5'-dimethyl benzopelargonolactone has been isolated from the chloroform fraction from the leaves of C. atropurpureus. The isolate was active against M. tuberculosis and could also increase the sensitivity of the pathogen to rifampicin. (38)
Bacteriostatic / Anti-Salmonella: Study evaluated the effect of an ethanol extract of Coleus atropurpureus L. Benth on S. enteritidis infection in mice. Results showed CA to be bacteriostatic and therapeutic at studied doses for S. enteritidis in mice. (39)
Anti-Inflammatory / Inhibition of Nitric Oxide Production / Leaves: Study evaluated the anti-inflammatory activity of ethanol extract, ethyl acetate, and water fraction of P. scutellarioides leaves using in vitro nitric oxide inhibitory assay on lipopolysaccharide-induced macrophage cells. Results showed the ethanol extract, EA and water fractions with IC50s of 76.46, 327.58 and 286.58 µg/mL, respectively. The ethanol extract showed most potency. (40)
Immunostimulant / Leaves: Study evaluated the immunostimulatory activity of ethanol extract and fractions from P. scutellarioides leave in male Wistar rats. Cellular immunity was conducted by a carbon clearance method compared to commercial immunostimulant containing other standardized plant extract. Results showed the leaves extract produced a significant increase in the phagocytic index compared to the fraction. According to the phagocytosis index, the extract classifies as a powerful immunomodulator candidate. (41)
Total Anthocyanin Content / Anthocyanidin / Leaves: The color of leaves may be due to anthocyanin pigments. Study evaluated the total anthocyanin content in P. scutellarioides leaves. Identification of anthocyanidin was done by maceration using ethanol acidified by concentration HCl 0.5% followed by liquid-liquid extraction by n-hexane, ethyl acetate, and water. Results showed total anthocyanin content was 0.435 mg/g pf wet weight of leaves calculated as cyanidin-3-glucoside. Spectrum analysis showed the presence of cyanidin. (42)

Availability
- Wild crafted.
- Ornamental cultivation for its colorful leaves.

Updated March 2021 / December 2017 / May 2015

PHOTOS / ILLUSTRATIONS
Photos © Godofredo Stuart / StuartXchange

Additional Sources and Suggested Readings
(1)
Diastereomeric Diterpenes from Coleus blumei / Consolacion Ragasa et al / CHEMICAL & PHARMACEUTICAL BULLETIN • Vol. 49 (2001) , No. 7 927 / doi:10.1248/cpb.49.927
(2
Antioxidant Activity of Coleus Blumei, Orthosiphon Stamineus, Ocimum basilicum and Mentha arvensis from Lamiaceae Family / Zuraini Zakaria et al / International Journal of Natural and Engineering Sciences 2 (1): 93-95, 2008
(3)
POTENTIAL USE OF HERBAL ANTHELMINTICS AS ALTERNATIVE ANTIPARASITIC DRUGS
FOR SMALL HOLDER FARMS IN DEVELOPING COUNTRIES
/ Satrija F et al / Livestock Community and Environment. Proceedings of the 10th Conference of the Association of Institutions for Tropical Veterinary Medicine, Copenhagen, Denmark, 2001
(4)
Coleus forskohlii
/ Healthline
(5)
Biological Activities of Sterols and Triterpenes from the Leacves of Coleus blumei Benth. / Rofe-Amor P. Obena and Amelia P Guevara / Institute of Chemistry, University of the Philippines, Diliman
(6)
Lamiacea/Solenostemon - Solenostemon scutellarioides (L.) Codd. LAMIACEAE / PLANTS FOR USE
(7)
Coleus (Coleus forskohlii) / Keri Marshall / Integrative Practitioner

(8)
Coleus blumei bentham-coleus
/ PsychoTropia
(9)
Extraction of antioxidant, phenolic content and minerals of coleus blumei leaves by boiling /
Norhidayah , Saat (2009) / UMP Research and Publication Repository
(10)
Coleus atropurpureus / The Plant List

(11)
Solenostemon scutellarioides / Wikipedia

(12)
Sorting Plectranthus names / /Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1995 - 2020 The University of Melbourne.
(13)
The determination of quercetin in Plectranthus scutellarioides (L.) R.Br. leaves extract and its In Silico Study on Histamine H4 Receptor
/ Moelyono Moektiwardoyo, Jutti Levita*, Syafrudin Purnama Sidiq, Khoziah Ahmad, Resmi Mustarichie, Anas Subarnas and Supriyatna / Majalah Farmasi Indonesia, 22(3), 191– 196, 2011
(14)
Maternity and medicinal plants in Vanuatu I. The cycle of reproduction / G. Bourdy and A. Walter / Journal of Ethnopharmacology, 37 (1992) 179-196 179 Elsevier Scientific Publishers Ireland Ltd.
(15)
Selenium Treatment Mitigates the Effect of Lead Exposure in Coleus Blumei Benth
/ Juhong Yuan, Mianhao Hu* and Zaohong Zhou / J Environ Anal Toxicol 2013, 3:6
(16)
AKTIVITAS ANTIMALARIA (IN VIVO) KOMBINASI BUAH SIRIH (Piper betle L), DAUN MIYANA (Plectranthus scutellarioides (L.) R. BR.) MADU DAN KUNING TELUR PADA MEN CIT YANG DIINFEKSI Plasmodium berghei / Yun Astuti Nugroho / Bulletin of Health Research. 2012;39(3 Sep)
(17)
Plectranthus scutellarioides (L.) R.Br. / Synonyms / The Plant List
(18)
Plectranthus scutellarioides / Useful Tropical Plants
(19)
Phytochemical screening and Partial Characterization through GC-MS of Leaf Crude Extract of Plectranthus scutellarioides (Mayana), and Plectranthus amboinicus (Oregano) and their Larvicidal Activity Against 2nd – 3rd Instar Larvae of Aedes aegypti in Comparison to Azadirachta indica / Hazel Ann L. Mariano, Daisy R. Sucaldito and Theresita V. Atienza /
(20)
Mayana ( Coleus blumei ) Leaves Ointment in Wound Healing of Albino Rats ( Rattus albus ) / Marvarieley Jean Moron, Liwayway H Acero Ed.D / International Journal of Food Engineering, June 2017; Vol 3, No 1: pp 18-22 / Presented at the DLSU Research Congress 2017
(21)
Pharmacological Activities of Plectranthus scutellarioides (LL..)) R..BBr Leaves Extract on Cyclooxygenase and Xanthine Oxidase Enzymes / Jutti Levita, Sri Adi Sumiwi, Tiara Indah Pratiwi, Ekky Ilham, Syafrudin Purnama Sidiq and Moelyono Moektiwardoyo / Journal of Medicinal Plants Research, 25 May 2016; 10(20): pp 261-269
(22)
Review Article: Coleus Species: Solenostemon scutellarioides / Manoj Suva, Anikit M Patel, Neeraj Sharma / Planta Activa, 2015
(23)
Effects of Miana (Coleus scutellariodes (L) Benth) to Expression of mRNA IL-37 in Balb/c Mice Infected Candida albicans / Marni Karo, Mochammad Hatta, WaOde Salma, Ilhamjaya Patellongi, Rosdiana Natzir / Pharmacogn J. 2018; 10(1):pp 16-19
(24)
Potential of Different Coleus blumei Tissues for Rosmarinic Acid Production / Natasa Bauer, Rosemary Vukovic, Sasa Likic, and Sibila Jelaska / Food Technol biotechnol., Mar 2015; 53(1): pp 3-10 / doi: 10.17113/ftb.53.01.15.3661 / PMID: 27904326
(25)
Coleus Poisoning in Dogs
(26)
Coleus scutellarioides / R C CAmabie, J Ash / Fijian Medicinal Plants
(27)
Isolation, Identification, and Characterizatic of Essential Oil of Iler (Plectranthus scutellarioides (L.) R.Br. Leaves / Resmi Mustarichie, Moelyono Moektiwardojo, Winda Apriani Dewi / J Pharm Sce & Res,m 2017; 9(11): pp 2218-2223 / ISSN: 0975-1459
(28)
New diterpenoid glucoside and flavonoids from Plectranthus scutellarioides (L.) R.Br. / R Kubinova, M Gazdova, Z Hanakova, S Jurkaninova, S Dall'Acqua, J Cvacka, O Humpa / South African Journal of Botany, Jan 2019; Vol 120: pp 286-290 / DOI: https://doi.org/10.1016/j.sajb.2018.08.023
(29)
Three new abietane-type diterpenoids from the leaves of Indonesian Plectranthus scutellarioides / Takuyo Ito, Senda Kartika Rakainsa, Khoirun Nisa, Hiroyuki Moruta / Fitoterapia, June 2018; Vol 127: pp 146-150 / DOI: https://doi.org/10.1016/j.fitote.2018.02.013
(30)
Antidiabetic Activity of Fractions and Subfraction of Iler (Plectranthus scutellarioides L. R.Br.) Leaves on Diabetic Mice Induced by Alloxan / Salaeh A, Augusti R S, Susilawati Y, Sumiwi S A, and Moektiwardojo M / Research Journal of Chemistry and Environment, Jan 2018; 22(SI4)
(31)
Pletranthus scutellarioides (L.) Reduces the Rectal Temperature of Diphtheria-Pertusis-Tetanus Vaccine-Induced Mice / Yudha Prabowo, Nyi M Saptarini, Sri A Sumiwi, Jutti Levita, Imam A Wicaksono, Moelyono Moektiwardoyo / Pharmacology and Clinical Pharmacology Research / eISSN: 2614-0020 / pISSN: 2527-7332 / DOI: https://doi.org/10.15416/pcpr.v4i2.23690
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Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides / Sylvian Cretton, Noemie Saraux, Aymeric Monteillier, Davide Righi, Laurence Marcourt, Gregory Genta-Jouve, Jean-Luc Wolfender, Muriel Cuendet, Philippe Christen / Phytochemistry, Oct 2018; Vol 154: pp 39-46 /
DOI: http://doi.org/10.1016/j.phytochem.2018.06.012
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IgM antibody and colony fungal load impacts of orally administered ethanol extract of Plectranthus scutellarioides on mice with systemic candidiasis / Marni Br Karo, Mochammad Hatta, Ilhamjaya Patellongi, Rosdiana Natzir, Titus Tambaip / Journal of Pharmacy & Pharmacognosy Research, 2018; 6(11): pp 27-34 / ISSN: 0719-4250
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Influence of leaf temperature and blue light on the accumulation of rosmarinic acid and other phenolic compounds in Plectranthus scutellarioides (L.) / Oliver S Dörr, Benno F Zimmermann, Stine Kögler, Heiko Mibus / Environmental and Experimental Biology, Nov 2019; Vol 167: 103830 /
DOI: https://doi.org/10.1016/j.envexpbot.2019.103830
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Green Ultrasound Assisted Extraction of trans Rosmarinic Acid from Plectranthus scutellarioides (L.) R.Br. Leaves / Duangjai Tungmunnithum, Laurine Garros, Samantha Drouet, Sullivan Renouard, Eric Laine, Christopher Hano / Plants, 2019; 8(3) / DOI: https://doi.org/10.3390/plants8030050

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Ethnobotanical documentation of medicinal plants used by the Ati tribe in Malay, Aklan, Philippines / Cecilia Salugta Cordero, Antonio Ligsay, Grecebio Jonathan Duran Alejandro / Journal of Complementary Medicine Research, 2018
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Constituents and antibacterial activity of leaf essential oil of Plectranthus scutellarioides / Pakeeza Aziz, Nadeem Muhammad, Azeem Intisar, Muhammad amin Abid et al / Plant Biiosystems - International Journal Dealing with all Aspects of Plant Biology / DOI: https://doi.org/10.1080/11263504.2020.1837279
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THE ANTITUBERCULOSIS DRUG RIFAMPICIN IS ACTIVATED BY 2', 5'-DIMETHYL BENZOPELARGONOLACTONE FROM THE LEAF OF Coleus atropurpureus L. BENTH / Ahyar, Ahmad / Hasanuddin University Repository
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Effect of Coleus atropurpureus L. Benth Ethanol Extract on Salmonella enteritidis Infection in Mice (Mus musculus) / Tati Arianti, Raden Inna Fazrina dan Darmono / Seminar Nasional Teknologi Peternakan dan Veteriner 2007
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Inhibition of Nitric Oxide Production in Lipopolusacchardie-Induced Macrophages Cell by Plectranthus scutellarioides (L.) R.Br. Leaves / Syifa Ghiza Fakhruati, Musfiroh Ida, Moektiwardoyo M and Akmarina Citra Ayu / Research Journal of Chemistry and Environment, Jan 2018; 22(Special Issue 1)
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Immunostimulatory activity of Plectranthus scutellarioides (L.) R.Br. leaves ethanolic extract and its fraction on rat using carbon clearance method / Moektiwardoyo Moelyono, Siti Rositah, Agung Fitri Kusuma / Drug Invention Today, Nov 2019' 11(11): pp 2990-2995
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Total Anthocyanin Content and Indentification of Anthocyanidin from Plectranthus Scutellarioides (L.) R.Br. Leaves / Akmarina Citra Ayu, Musfiroh Ida, Moektiwardoyo Moelyono and Syifa Ghiza Fakhriati / Research Journal of Chemistry and Environment, Jan 2018; 22(Special Issue 1) : pp 11-17
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Comparison of two varieties of Plectranthus scutellarioides based on extraction method, phytochemical compound, and cytotoxicity / A D Astuti et al / J Phys: Conf. Ser. 1341 - 072012

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