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Family Euphorbiaceae
Banato
Mallotus philippensis Lam.
KAMALA


Other scientific names  Common names   
Croton philippinense  Apuyot (Sul.)  Pikal (Sbl.) 
Echinus philippinensis  Buas (Ilk.)  Rohini
Rottlera manilensis  Darandang (Tag.)  Sala (Tag., Bis.) 
Rottlera philippinensis  Kamala (Engl.)  Tafu (Ibn.)
  Kamela (Engl.) Tagusala (P. Bis) 
  Panagisen (Ibn.)  Tutula (Tagb.) 
  Panagisian (Ibn., Klg., Neg.)  Rottlera (Engl.) 
  Pañgaplasin (Ilk.)   

Botany
A tree growing to a height of 4 to 10 meters, with the branchlets, young leaves and inflorescence covered with brown hairs. Leaves are alternate, oblong-ovate, with a pointed tip and rounded base, 7 to 16 cm long, with toothed or entire margins. Upper surface of the leaf what two smooth glands; the lower surface, glaucous and hairy with numerous, scattered crimson glands. Male flowers are numerous, 3 mm in diameter, axillary, solitary or fasicled spikes, 5 to 8 cm long. Female flowers are in solitary racemes. Fruit is spherical, 6 to 8 mm in diameters, densely covered with red or crimson powder, with three cells, each containing a dark grey, rounded seed that is flattened on one side.

Distribution
In thickets and secondary forests at low altitudes.

Chemical constituents and properties
Considered antibacterial, anticancer, antihelminthic, antifertility, antispasmodic, astringent, contracepticeptive, laxative, vermifuge, and purgative and vulnerary.
Extract of kamala from the glands and hairs yielded a resin, a wax, and the crystalline compound rottlerin.
Kamala also contains a minute amount of essential oil, which when gently warmed emits a peculiar odor.
The principle constituent, rottlerin, is from the kamala resin.
Rottlerin (reddish-yellow resin), 47-80%; fixed oil, 5.83-24%; citric acid; mallotoxin; kamalin.
The seed contains a fixed oil, camul oil and a bitter glucoside.
According to Ayurveda, leaves are bitters, cooling and appetizer.
Fruit is anthelminthic, vulnerary, detergent, maturant, carminative.


Parts used and preparation
Leaves, bark and seeds.

Uses
Folkloric
Fungal skin infections: Pound leaves or seeds and apply on affected areas.
The red glands of the fruit is antiherpetic and antihelminthic.
Poulticed leaves and bark used for skin diseases – ringworm and scabies; poulticed seeds used for wound healing.
Powder taken with milk for tapeworms, repeated as necessary.
In india, used for bronchitis, abdominal diseases, spleen enlargement.
Elsewhere, used for constipation, anorexia, cancers, dermatosis, cramps, dysmenorrhea.
Others
Kamala, the powder obtained from the glands and hairs, besides its medicinal properties, is valued as a dye.
Dye is used for coloring silk and wool.
The oil derived from the seeds is used in paints and varnishes, as hair-fixer, and ointment additive.
Antioxidant for ghee and vegetable oils.
Wood pulp used for making writing and printing paper.


Studies
Antifilarial Activity:
The effect of aqueous and alcoholic extracts of the leaves of Mallotus philippensis was studied on the spontaneous movements of the whole worm and nerve-muscle preparation of Setaria cervic and on the survival of microfilariae in vitro.
Antimicrobial:
In an ethnopharmacological screening in Nepal, the bark from Mallotus philippensis was found to be active against gram-positive and gram-negative bacteria.
* Anti-allergic:
Two new phloroglucinol derivatives were isolated from the fruits of Mallotus philippensis. They inhibited histamine release from rat peritoneal mast cells suggesting the new phloroglucinol derivaties have anti-allergic effects.
Antibacterial / Phytochemical:
(1) Study showed excellent inhibition with chloroform and methanol extracts of the stem barkn testing with E coli, K pneumonia, P aeruginosa, S typhi and B subtilis, (2) Mallotus philippinensis was one of plants in a study of 61 Indian medicinal plants that exhibited antimicrobial properties, supporting its folkloric use as antimicrobial treatment for some diseases.
Antifertility: Study showed when females treated with Kamala seed extract were mated with non-treated males, rate of infertile mating increased in a dose-dependent manner with reduced pregnancy rate and number of implantation sites. Data indicate, Kamala reduced levels of FSH and LH and affected various reproductive parameters of female rats.

Availability
Wild-crafted.



Additional Sources and Suggested Readings
(1)
An etheral extract of Kamala (Mallotus philippinensis (Moll.Arg) Lam.) seed induce adverse effects on reproductive parameters of female rats / Sonu Chand Thakur et al / Reproductive Toxicology • Volume 20, Issue 1, May-June 2005, Pages 149-156 / doi:10.1016/j.reprotox.2004.12.008
(2)
Kamala or kamopillaka (Mallotus philippinensis Muell.) / Pankaj Oudhia / Society for Parthenium Management (SOPAM)
(3)
Antifilarial activity of Mallotus philippensis Lam. on Setaria cervie (Nematoda: Filarioidea) in vitro. / Singh R, Singhal KC, Khan NU / Indian J Physiol Pharmacol. 1997 Oct;41(4):397-403.
(4)
Antimicrobial activities of southern Nepalese medicinal plants / R. S. L. Taylora et al / Journal of Ethnopharmacology • Volume 50, Issue 2, February 1996, Pages 97-102 / doi:10.1016/0378-8741(95)01335-0
(5)
Anti-allergic agents from natural sources / Anti-allergic activity of new phloroglucinol derivatives from Mallotus philippensis (Euphorbiaceae) / DAIKONYA Akihiro; KATSUKI Shigeki et al / Chemical and pharmaceutical bulletin • 2002, vol. 50, no12, pp. 1566-1569
(6)
Phytochemical screening and antibacterial evaluation of stem bark of Mallotus philippinensis var. Tomentosus / K Moorthy et al / African Journal of Biotechnology Vol. 6 (13), pp. 1521-1523, 4 July 2007 /AJB ISSN 1684–5315
(7)
Search for antibacterial and antifungal agents from selected Indian medicinal plants. / Kumar V P et al / J Ethnopharmacol. 2006 Sep 19;107(2):182-8. Epub 2006 Mar 27.
(8)
Handbook of medicinal herbs / James A. Duke, Mary Jo Bogenschutz-Godwin


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