Cadena-de-amor is a climbinhg, somewhat woody, perennial
vine, with stems attaining a length of 10 meters. Leaves are alternate, ovate
to oblong-ovate, with cordate base, serrate margins, up to 10 centimeters long.
Flowers are borne in racemes at the upper axils of the terminal parts
of the branches, the rachis of the racemes producing tendrils. Flowers are white or pale to deep pink, up to 2 centimeters long, with 5-parted
and persistent perianth. Fruit is an ovoid achene, about 1 centimeters long, broad at the
base, narrowing towards the tip, loosely surrounded by the persistent
lobes of the flower.
- Widespread in the Philippines.
Usually cultivated in gardens.
- Some have escaped cultivation to become noxious weeds.
Propagated by seeds or cuttings.
- Native to Mexico.
- Found in tropical Asia, Africa, Caribbean and the Americas.
- Phytochemical screening of plants flowers extracts yielded alkaloids, quinines, resins, tannins, fixed oils, flavonoids, fats, saponins phenolic compounds, proteins, and carboxylic acids.
- Screening of methanol flower extracts yielded phenol, flavanoids, saponins, amino acids, triterpenoidal sapogenins, tannins, xanthoproteins, carboxylic acids, coumarins and carbohydrates.
- A methanol extract of
the aerial part of the flower yielded (1) n-hentriacontane (1), ferulic
acid (2), 4-hydroxycinnamic acid (3), quercetin-3-rhamnoside (4), and
kaempherol-3-glucoside (5) along with ?-sitosterol, ?-sitosterol-glucoside
COX inhibitory properties and antithrombin activities.
Studies have shown anti-thrombin,
analgesic, anti-inflammatory, anti-diabetic and lipid peroxidation inhibitiory
Bark, fruit, leaves and
- In some parts of the world, the tubers and flowers are consumed as food.
- In Thailand, leaves and flowers, flour-coated and fried, are served with noodles.
- In the Philippines,
an isolated report of use by Ifugao-migrants in the foothills of the
Sierra Madre for wound closure. (Link)
- In Trinidad
and Tobago, used
for diabetes, low blood pressure, and as a heart tonic.
- Aerial portion of the flowers used in decoctions as a cold remedy.
- In other countries decoction of aerial parts used as a remedy for colds
and pain relief.
- In Jamaica, decoction of aerial parts
traditionally used for prevention of cough and flu-related pains.
Flower clusters popular for use in flower
and foliage arrangements for social functions.
• Phytochemicals / Lipid peroxidation and Selective COX2 Enzyme Inhibition: Studies yielded n-hentriacontane (1), ferulic acid
(2), 4-hydroxycinnamic acid (3), quercetin-3-rhamnoside (4), and kaempherol-3-glucoside
(5) along with ß-sitosterol, ß-sitosterol-glucoside and d-mannitol.
Results showed LPO and COX inhibitory activities.
• Antithrombin activity: A chromogenic
bioassay was utilized to determine the antithrombin activity of methylene
chloride and methanol extracts prepared from 30 plants of central Florida.
Antigonon leptopus was one of seven extracts that demonstrated activity of 80%
or higher in the bioassay system.
• Analgesic / Antiinflammatory: (1)
showed the extract of A. leptopus possesses significant analgesic and
anti-inflammatory effect. (2) Study reports isolation of a compound
from A. leptopus tea with selective COX-2 enzyme and LPO inhibitory
Antifilarial: Extract study showed A leptopus possessed
significant juvenile hormone analogue activity against Culex quinquefasciatus.
• Anti-Diabetic: Study of the methanolic extract of aerial parts of Antigonon leptopus showed significant antidiabetic activity and supports its traditional claim of use in diabetes and its associated complications.
• Antibacterial: Study evaluated the antibacterial properties of flower extracts of Antigonon leptopus. The ethanol and chloroform extracts exhibited significant concentration-dependent inhibition against B. subtilis, Bacillus peritlis and Salmonella typhi.
• Antimicrobial / Dental Pathogens: Study showed the flower extracts of Antigonon leptopus showed potent antimicrobial activity against common human dental pathogens - Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa and Micrococcus albus.
Seeds in the cybermarket.