Family Fabaceae
Dapdap
Erythrina variegata Linn. var. orientalis (Linn.)
INDIAN CORAL TREE

Other scientific names  Common names
Erythrina corallodendron Linn . Andorogat (Bik.) 
Tetradapa javanorum Osbeck . Bagbag (Ilk.)
Erythrina indica Linn . Andorogat (Bik.) 
Erythrina carnea Blanco . Bagbok (Ibn.)
  Dapdap (Tag., Pamp., Bik., Bis.)
  Dubdub (Ilk.)
  Kabrab (Bik.)
  Karapdap (Tag.)
  Kasindak (Tag.)
  Sabang (Bon.)
  Sulbang (Pamp.)
  Vuvak (Ibn.)
  Tiger's claw (Engl.)
  Indian coral tree (Engl.)

Botany
· A deciduous tree reaching a height of 15 m, the branches and the branchlets stout and armed with short, few to many sharp prickles.
· Leaves: leaflets broadly ovate and 8 to 18 cm long, with pointed tip and broad base.
· Flowers: calyx about 4 cm long and minutely Toothed at the tip, the mouth being very oblique. Petals brightly red and shorter than the calyx, the standard being 7 to 9 cm long and the wings and keels subequal. Stamens 10, upper filaments free nearly to the base or more or less connate with others. Ovary many-ovuled, style incurved. Racemes terminal, hairy, dense and up to 2.5 cm long. Papilionaceous flowers large and numerous.
· Fruits: pods, 10 to 25 cm long, 1.5 to 2 cm in diameter and distinctly constricted between the seeds.

Distribution
Shoreline; and frequently planted inland throughout the Philippines.

Part utilized
Bark and leaves.
Remove spines from bark after collection, rinse, sun-dry.

Characteristics and Pharmacological Effects
• Antirheumatic. Beneficial for the circulation and nerves. Prepared drug tastes bitter, neutral in effect.
• The bark is bitter, acrid, thermogenic, anti-inflammatory, sedative, carminative, digestive, anthelminthic, rejuvenating, laxative, diuretic and expectorant.
• The leaves are bitter, diuretic, laxative, emmenagogue, stomachic and anthelmintic.

Uses
Folkloric
• Rheumatic lumbar and leg pain - take 9 to 15 gms dried bark in decoction or in the form of alcohol (wine) infusion.
• Infantile convulsion, ascariasis: Take 2.5 to 3 gms pulverized leaves in the form of snuff.
• In India and China, the bark and leaves are used in many traditional medicinal concoctions. Paribhadra, an Indian preparation, destroys parasites and relieves joint pains. Honeyed leaf juice is used for tapeworm and roundworm diseases. The juice also helps stimulate lactation and menstruation. A poultice of leaves is used for rheumatic joints.

Studies
Antibacterial:
Antibacterial activity of isoflavonoids isolated from Erythrina variegata against methicillin-resistant Staphylococcus aureus: 16 isoflavonoids isolated from Erythrina variegata was screened for antibacterial activity against methicillin-resistant Staph aureus. Of the active compounds, erycristagallin and orientanol B showed the highest anti-MRSA activity.
Antibacterial / Dental Caries Prevention: Study isolated t compounds from EV with antibacterial property against cariogenic oral bacteria. Among them was erycristagallin, a potential phytochemical agent for the prevention of dental caries by inhibiting the growth of cariogenic bacteria.

Anti-osteoporotic Effect:
Study showed that E. variegata could suppress the high rate of bone turnover induced by estrogen deficiency and improve the biomechanical properties of bone in the lab rats.
Erythrina - chemical and pharmacological evaluation II: Alkaloids of erythrina variegata L
: The study showed characteristic pharmacological effects: neuromuscular blocking, smooth muscle relaxant, CNS depressant, anticonvulsant effects supporting the indigenous use of the plants.

Trypsin / Proteinase Inhibitors:
Study indicate that E. variegata proteinase inhibitors possess different potency toward serine proteinases in blood coagualation and fibrinolytic systems.
Antimicrobial / Cytoxicity:
Study isolated five compounds from the methanol extract of stem bark of EV: epilupeol, 6-hydroxygenistein, 3ß, 28-dihydroxyolean-12-ene, epilupeol, stigmasterol. Diiferent partitionates showed mild to moderate antimicrobial activity and varying degrees of cytotoxicity.

Availability
Wild-crafted.
 



Additional Sources and Suggested Readings
((1)
Erythrina variegata / NFTA / Winrock
(2)
Indian Medicinal Plants
(3)
Antibacterial activity of isoflavonoids isolated from Erythrina variegata against methicillin-resistant Staphylococcus aureus
(4)
Anti-osteoporotic effect of Erythrina variegata L. in ovariectomized rats / Journal of Ethnopharmacology Vol 109, Issue 1, 3 January 2007, Pages 165-169 / doi:10.1016/j.jep.2006.07.005
(5)
Erythrina - chemical and pharmacological evaluation II: Alkaloids of erythrina variegata L
http://www3.interscience.wiley.com/journal/113338387/abstract
(6)
Human erythrocyte specific lectin from the seeds of Indian coral tree, Erythrina variegata L.
http://www.ias.ac.in/jarch/jbiosci/5/25-30.pdf
(7)
Antibacterial property of isoflavonoids isolated from Erythrina variegata against cariogenic oral bacteria
/ Phytomedicine : international journal of phytotherapy and phytopharmacology / 2003-; vol 10 (issue 5) : pp 427-33

(8)
Inhibitory potency of Erythrina variegata proteinase inhibitors toward serine proteinases in the blood coagulation and fibrinolytic systems / NAKAGAKI T et al / Bioscience, biotechnology, and biochemistry / 1996, vol. 60, no8, pp. 1383-1385
(9)
PHYTOCHEMICAL AND BIOLOGICAL INVESTIGATIONS OF ERYTHRINA VARIEGATA / Saudi Pharmaceutical Journal, Vol. 15, No.2, April 2007