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Family Compositae
Dila-dila
Elephantopus scaber
PRICKLY-LEAVED ELEPHANT'S FOOT
Ti Tan-t'ou


Dila-dila is a shared common name by many different species of plants: (1) Onychium siliculosum: Buhok-virgin (Tag.); dila-dila (Tag) (2) Nopalea cochinellifera: Dila-dila (Ilk.); dilang baka (Tag.) (3) Elephantus scaber: Dila-dila (Tag.), kabkabron (Ilk.); prickly leaved elephant's food (Engl.) (4) Pseudoelephantopus spicatus: Dila-dila (Tag.); dilang-aso (Tag.) Kabkaron (Ilk.) Plus, close variations and use of "dila" for other plants further add to the confusion and difficulty in the list of common names: Dila-dilag (Spilanthes acmella); Dilang aso (P. spicatus); Dilang-baka (N. Cochinellifera); Dilang-boaia, dilang-halo (Aloe vera); Dilang-butiki (Dentella repens); Dilang-butiki (Hedyotis philippensis); Dilang-usa (Trichodesma zeylanicum); and Diladila (Cordyline roxyburghiana).


Common names
Dila-dila (Tag.)
Kabkabron (Ilk.) 
Lengua de vaca (Sp.) 
Tabatabakohan (Tag.) 
Ti Tan-t'ou (Chin.)
Prickly-leaved elephant's foot (Engl.) 


Description
· A rather coarse, rigid, erect, hairy herb 30 to 60 cm high. Stems forked, and the few and stiff.
· Leaves: mostly in basal rosette and oblong-ovate to oblong-lanceolate, 10-25 cm in length and often very much notched on the margins. Those on the stem few and much smaller.
· Flowers: Corolla 8-10 mm long, purple. Flowering heads borne in clusters at the end of the branches and usually enclosed by 3 leaflike bracts which are ovate to oblong-ovate, 1 to 1.5 cm long, and heart-shaped at the base. The flowering heads many-crowded in each cluster. Each head comprises about 4 flowers. Involucral bracts 8 to 10 mm long.
· Fruits: achenes, ribbed. Pappus from 4 to 6 mm long with rigid bristles.

Distribution
Most likely introduced. Common in open ; grasslands and waste places Common in provinces of La Union, Bulacan, Rizal, Bataan, Laguna, Quezon, and Mindoro.

Part utilized and preparation
· Entire plant.
· Collect from January to September.
· Wash, cut in pieces, dry under the sun.

Chemical constituents, characteristics and pharmacological effects:
Bitter, antipyretic, antiinfection, astringent, tonic, diuretic.
Flowers are astringent, ophthalmic, aphrodisiac and expectorant.
Study for essential oil revealed: hexadecanoic acid, 43.3%; isopropyl dimethyl tetrahydronaphthalelol, 14.1%; b-sesquiphellandrene, 8.3%; octadecadienoic acid, 5.5%; and phytol, 5.2%.


Uses
Folkloric
· Upper respiratory afflictions: Colds, flu, tonsillitis, laryngopharyngitis, conjunctivitis.
· Snakebites, furuncle swellings, eczema, ulcer the lower limb.
· Nephritis, beriberi, edema, hepatitis, chest pains, fever. scabies.
· Dosage: 15 to 30 gms dried material in decoction.
· Pounded fresh material is applied as poultice for snakebites, furuncle swelling.
· Juice of pounded leaves applie to scalp to slow down hair loss.
· Decoction of fresh material is used as wash for eczema.
· Decoction of roots and leaves for dysuria, diarrhea, bronchitis, fevers.
· Decoction of root for hemorrhoids.
· Poultice of leaves for skin diseases.
· Flowers for liver problems, ophthalmopathy, bronchitis, cough.


Studies
Essential Oil:
Study of the chemical composition of the sssential oil of Elephantopus scaber from Southern China identified 21 compounds. The major constituents were hexadecanoic acid (42.3%), isopropyl dimethyl tetrahyudronaphthalenol (14.1%), ß-sesquiphellandrene (8.3%), octadecadienoic acid (5.5%) and phytol (5.2%).
Anti-Diabetes:
(1) Effect of Crude Extract and Fractions from E. Scaber on Hyperglycemia in Streptozotocin-diabetic Rats: Study indicates E. scaber has an antihyperglycemic action and is a source of potent hypoglycemic compounds. (2) Effect of E. scaber leaf extract on STZ-induced diabetic rats showed the methanol extract exhibited better hyperglycemic action than the hexane and ethyl acetate extracts. (3) An acetone extract exhibited significant anti-diabetic activity by reducing blood glucose and restoring the insulin levels in STZ-induced diabetic rats.
Hepatoprotective:
Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury: Study suggests the hepatoprotective effect of the medicinal plant.
Antitumor / Anti-Chemical Carcinogenesis: (1) Study indicates antitumor activity of E. scaber sesquiterpene lactones. (2) Study of E scaber on skin papillomas induced by DMBA and croton oil in mice showed tumor inhibitory activity of the active fraction against chemically induced tumors and an ability to inhibit the development of solid tumors.
Antibacterial:
(1) A Novel Terpenoid from Elephantopus Scaber – Antibacterial Activity on Staphylococcus Aureus: A new terpenoid from E. scaber extract showed antibacterial activity and suggests that it can act as a drug for bacterial infections
. (2) Result of study confirmed the antimicrobial potential of the ethyl acetate extract of E. scaber. (3) Study showed strong in vitro antibacterial activity of terpenoid derivatives against ES beta-lactamase-producing methicillin resistant Staphylococcus aureus.
Antiinflammatory: 'Teng-Khia-U,' a Taiwanese folk medicine derived from E. scaber, E. mollis and Pseudoelephantopus spicatus was evaluated for its antiinflammatory activities. Results indicated pre-treatment with Teng-Khia-U significantly inhibited the carrageenan-induced arthritis and suppressed the development of chronic arthritis induced.

Availability
Wild-crafted. 


Additional Sources and Suggested Readings
(1)
Chemical Composition of the Essential Oil of Elephantopus scaber from Southern China / Li Wang et al / Z. Naturforsch. 59c, 327Ð329 (2004)
(2)
Effect of Crude Extract and Fractions from E. Scaber on Hyperglycemia in Streptozotocin-diabetic Rats
(3)
Comparative Studies on the Different Leaf Extracts of Elephantopus Scaber.L on STZ-Induced Diabetic Rats / Daisy P, Lily Vargese, Cecilia Edel Priya / European Journal of Scientific Research / ISSN 1450-216X Vol.32 No.3 (2009), pp.304-313
(4)
Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury
(5)
Indian Medicinal Plants / Arya Vaidya Sala / Kottakkal, P. K. Warrier
(6)
Antitumor activities of the four sesquiterpene lactones f from m Elepephantopus scaber L.
(7)
A Novel Terpenoid from Elephantopus Scaber – Antibacterial Activity on Staphylococcus Aureus
(8)
A study of the antimicrobial activity of Elephantopus scaber
/ K Avani, S Neeta / ndian J Pharmacol [serial online] 2005 [cited 2009 Jul 15];37:126-7
(9)
Anti-inflammatory effects of Taiwan folk medicine ‘Teng-Khia-U’ on carrageenan- and adjuvant-induced paw edema in rats / Chin-Chuan Tsai and Chun-Ching Lin / Journal of Ethnopharmacology Vol 64, Issue 1, 1 January 1998, Pages 85-89 / doi:10.1016/S0378-8741(98)00108-1

(10)
A novel Steroid from Elephantopus scaber L. an Ethnomedicinal plant with antidiabetic activity / P Daisy et al / Phytomedicine, Vol 6, Issues 2-3, March 2009, pp 252-257 / doi:10.1016/j.phymed.2008.06.001
(11)
Evaluation of Elephantopus scaber on the inhibition of chemical carcinogenesis and tumor development in mice / Geetha B S et al / Pharmaceutical Biology (Formerly International Journal of Pharmacognosy), Vol 48, Number 3, March 2010 , pp. 342-348(7)
(12)
Evaluating the Antibacterial Activity of Elephantopus scaber Extracts on Clinical Isolates of β-lactamase Producing Methicillin Resistant Staphylococcus aureus from UTI Patients / R Jasmine, P Daisy and B N Selvakumar / Int. J. Pharmacol., 3: 165-169. / DOI: 10.3923/ijp.2007.165.169


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