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Family Compositae
Gagatang
Sonchus oleraceus Linn.
SOW THISTLE

Scientific names Common names
Sonchus oleraceus Linn. Gagatang (Ig.)
Hieracium oleracerum Linn. Common sowthistle (Engl.)
Lactuca oleracerea Linn. Milkweed (Engl.)
  Milk thistle (Engl.)
  Smooth sow thistle (Engl.)
  Swinles (Engl.)
  Sow thistle (Engl.)
   

Etymology
The common name 'sow thistle' derives from its attractiveness to swine and the similarity of its leaf to the pig's ear. The scientific name's latin roots are: sonchus, hollow stem and oleraceus, delectable nature, herb used in cooking.

Botany
Gagatang is an herb, erect, annual, milky, hairy or slightly glandular, growing 40 to 80 cm high. Leaves are oblong to lanceolate, 10 to 20 cm long, coarsely and lyrately lobed; the lobes somewhat reflexed and toothed, the terminal ones large, the lateral pointing downwards, and those of the stem clasping at the base. Heads are peduncled, about 1 cm long. Bracts are smooth, thin and green. Flowers are numerous and yellow. Achenes are nearly 3 mm long, compressed, ribbed and rough.

Distribution
Found in the Benguet subprovinces, Rizal and Laguna provinces in Luzon.
In waster places, along trails, old gardens, on talus slopes at altitudes of 1,200 to 2,000 meters.

Constituents
- Contains fixed oil with stearic and palmitic acids, ceryl-alcohol, invert sugar, choline, tartaric acid.
- Milky juice contains oxydase, coautchoue, mannite, l-inosite, etc.
- Phytochemicals of aqueous extracts yielded sugar reducers, phenolic compounds, tannins, flavonoids and coumarins.
- Study yielded four sesquiterpene glycosides - sonchusides A, B, C and D together with five known glycosides - glucozaluzanin C, macrocliniside A, crepidiaside A and picrisides A and C.

Parts used
Stem, leaves, gum, juice.

Uses

Folkloric
- Brownish gum formed by the evaporation of the common sow thistle, when taken internally in a dose of two to four grains, acts as a "powerful hydragogue cathartic" with strong effects on the liver, duodenum and colon. Its effects resemble elaterium, producing large and watery discharges, thus an effective agent in ascites and hydrothorax. However, it may cause griping like senna and produce tenemus like aloes. To counteract that effect, the gum is administered with manna, aniseed, and carbonate of magnesia, or with stimulants and aromatics
- Infusion of leaves and roots used by the natives of Bengal as tonic and febrifuge.
- In Indochina, stems used as sedative and tonic.
- In Italy, used as a laxative and diuretic.
- Juice of the plant used for cleaning and healing ulcers.
- In Brazilian folk medicine, used as a general tonic.


Studies
Antidepressant:
Study of S oleraceus extracts in mice showed evidence of an antidepressant-like effect comparable to that of amitriptyline (10mg/K p.o.).
Antinociceptive: Extracts of SO markedly demonstrated antinociceptive action in mice, supporting previous claims of traditional use. At 300 mg/kg, it had a stronger antinociceptive effect than indomethacin (5 mg/kg) and morphine (10 mg/kg).
Anxiolytic: Study of extract of aerial parts showed anxiolytic effects in mice similar to clonazepam (0.5 mg/kg).
Phytochemicals / Low Toxicity: Study of aqueous extracts showed phenolic compounds, tannins, flavonoids and coumarins. Toxicity test on Artemia salina indicated low toxicity.
Antioxidant / Cytotoxicity: Study of SO extracts showed concentration-dependent antioxidant activity. The methanol extracts yielded the greatest the most phenolic and flavonoid contents. Cytotoxicity activity showed the ethanol extract had the best activity against the growth of stomach cancer cell.
Anti-Quorum Sensing / Antimicrobial: A study of 14 ethanolic extracts of different parts of 8 plants for antimicrobial and antiquorum sensing activity showed Sonchus oleraceus and Laurus nobilis to have superior activity against Chromobacterium violaceum. Quorum sensing is involved in microbial pathogenesis, and its inhibition may be a way of controlling bacterial infections with the advantage of reducing risks of resistance development.

Availability
Wild-crafted.
Extracts and supplements in the cybermarket.

Last Update July 2010

IMAGE SOURCE / Public Domain / Modified / File:Sonchus oleraceus Sturm49.jpg / Deutschlands Flora in Abbildungen / Johann Georg Sturm (Painter: Jacob Sturm / 1796 / Wikimedia Commons (2) File:Sivone.jpg / Archive of www.coloridellamurgia.it / Wikipedia

Additional Sources and Suggested Readings
(1)
Sonchus oleraceus / Wikipedia
(2)
Antidepressant-Like Activity of Sonchus oleraceus in Mouse Models of Immobility Tests / Fabiana Cardoso Vilela, Marina de Mesquita Padilha, Geraldo Alves-Da-Silva, Roseli Soncini, Alexandre Giusti-Paiva / Journal of Medicinal Food. February 2010, 13(1): 219-222 / doi:10.1089/jmf.2008.0303.
(3)
Evaluation of the antinociceptive activity of extracts of Sonchus oleraceus L. in mice. / Vilela F C, de Mesquita Padiha et al / J Ethnopharmacol. 2009 Jul 15;124(2):306-10. Epub 2009 May 3
(4)
Anxiolytic-like effect of Sonchus oleraceus L. in mice / Cardoso Vilela F et al /
J Ethnopharmacol. 2009 Jul 15;124(2):325-7. Epub 2009 May 3.
(5)
The antioxidant and cytotoxic activities of Sonchus oleraceus L. extracts / Yin Jie, Kwon, Gu-Joong, Wang, Myeong-Hyeon / Nutrition Research and Practice / v.1, no.3, 2007, pp.189-194 / KOI : KISTI1.1003/JNL.JAKO200735836553460
(6)
Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts / Reema al-Hussaini and Adel M Mahasneh / Molecules 2009, 14, 3425-3435; doi:10.3390/molecules14093425
(7)
Studies on Sesquiterpene Glycosides from Sonchus oleraceus L.(Pharmacognosy,Chemical) / Miyase Toshio and Fukushima Seigo / Chemical & pharmaceutical bulletin 35(7), 2869-2874, 1987-07-25


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