Family Mimosaceae
Ipil-ipil
Leucaena glauca Linn.
SANTA ELENA

Other scientific names Common names  
Mimosa glauca Linn.  Agho (P. Bis.) Kariskis (Ilk.)
Acacia glauca Wiild.. Aghog (P. Bis.) Komkompitis (Ilk.)
Leucaena glauca Linn.   Ipel (Tag.) Loyloi (S. L. Bis.)
Leucaena leucocephala Lam.   Ipil-ipil (Tag.) Santa Elena (Span.)
  Kabahero (C. Bis.) San Pedro (P. Bis.)
    Lead tree (Engl.)

Botany:
Small plant up to 15 m high; leaves alternate, twice compound, 15-25 cm, base of petiole enlarged; leaflets 9 to 18 pairs, 7 to 12 mm long, linear-oblong, unequilateral; flowering stalks axillary, 3.5 to 5 cm long. Flowers are whitist, in dense globule heads 2 to 3 cm in diameter. Fruit is an oblong or linear pod, strap-shaped, falttened, 12 to 18 cm long, 1 to 2 cm wide, papery, green turning brown and splits open along two edges when mature, several fruits develop from each flower head; seeds obovate, 5 to 8 mm long, 3 to 5 mm wide, shiny, brown.

Distribution:
Common plant widely distributed in the Philippines. Propagated by seeds or stem cuttings.

Parts utilized
Dried seeds

Constituents
• Fat, 8.68%; crude fiber, 22.59%; nitrogen-free material other than fiber, 9.78%; nitrogen, 6.42%; sucrose; water, 14.8%; ash, 4.2%.
• Seed contains the toxic amino acid mimosine.

Uses
Folkloric
Intestinal parasitism: ascaris and trichinosis.
Adults: 1 teasppon of powdered dried seeds, alone or mixed with condensed milk and followed by half a glass of water, taken as a single dose 2 hours after a meal; repeated after one week as needed.
Children: 7-8 years old: 1/4 to 1/2 teaspoon; 9-12 years old: 1/2 to 2/3 teaspoon.
Adverse effects: Abdominal pain, diarrhea.

Studies

• R&D on seed gum for a pharmaceutical substitute for the imported guar gum used as a binder in tablet formulation. In 1996, ipil-ipil was found to be an excellent liquid excipient as a suspending and thickening agent.
Inhibition of Growth of Hair by Mimosine: Loss of hair been reported in animals following ingesting of seeds and foliage and in women after consumption of LG seeds. The toxic principle is leucenol, an amino-acid (identical to the mimosine of Mimosa pudica) found primarily in the seeds of ipil-ipil, and in lesser amounts in foliage and stems.
Study of enhancement of sensitivity of hepatoma and lung cancer cells to chemotherapeutc drugs by mimosine from seeds of Leucaena Glauca Benth.

Availability
Wild-crafted.
 

 

Additional Sources and Suggested Readings
(1)
Inhibition of Growth of Hair by Mimosine
http://www.nature.com/nature/journal/v194/n4829/abs/194694b0.html
http://jn.nutrition.org/cgi/reprint/118/3/281.pdf
(2)
Study of enhancement of sensitivity of hepatoma and lung cancer cells
to chemotherapeutc drugs by mimosine from seeds of Leucaena Benth

http://www.ccmp.gov.tw/en/research/result_detail.asp?relno=51&selno=0&no=87&detailno=736