Kangkong is a smooth, widely spreading
vine, with the stems trailing on mud or floating on water. Leaves are
oblong-ovate, 7 to 14 centimeters long, with a pointed tip and heart-shaped or arrow-shaped
base, long petioled, the margins entire or angular, and sublobed. Peduncles are erect, 2.5 to 5 centimeters long, with 1 or 2 flowers, borne in the
axils of the leaves. Sepals are green, oblong, about 8 millimeters long. Corolla
is narrowly bell-shaped, about 5 centimeters long, and purplish; limb nearly white or pale pink purple, about 5 centimeters in diameter, the tube
deeper purple inside. Capsules are smooth and ovoid, about 1 centimeter long.
- Throughout the Philippines
in stagnant streams, fresh-water swamps, and pools.
- Probably introduced.
- Found throughout the tropics of the Old World.
- Extensively cultivated in southern China.
- Plant contains protein 1.6 %, fat 0.2%, and vitamins C3 and B2.
- Some major compounds from the plants are: nortropane alkaloids, calystegines B1; phenolic compounds N‐cis-Feruloyltyramine, N‐trans-feruloyltyramine, 3α,7β-O-D-di glycopyranosyl-dihydroquercetin and Isochlorogenic acid a, b and c. (see study below) (19)
- Compositional analysis of leaves yielded moisture 90%, protein 3%, fiber 0.9%, fat 0.4%, carbohydrate 4.3%, mineral matter 2%, nicotinic acid 0.6 mg/100g, riboflavin 120 mg/100g, vitamin C 137 mg/100g, vitamin E 11 mg/100g, and ash 1.4%. (20)
- Nutrient analysis of leaves (based on % dry weight) showed the leaves contained 3% protein, 4.5% total carbohydrate, 0.3% lipids, 78% moisture, 1.6% ash, 1.4% fiber and gross energy value of 141.4 Kj/g. Leaves yielded high amounts of essential amino acids (per 100g) 4765 mg: leucine 1365 mg/100g, tyrosine+phenylalanine 1124 mg/100g, lysine 682 mg, and threonine 606 mg. Minerals (per 100 g) were potassium 444 mg, calcium 163, sodium 159.8 mg, phosphorus 86, magnesium 52 mg, copper 5.3 mg, zinc 4.1 mg, iron 3.2 mg, and manganese 2.3 mg. (see study below) (23)
- Considered purgative, diuretic, antiepileptic, CNS depressant, anti-inflammatory, hypolipidemic, antimicrobial, anthelmintic, antidiabetic.
Young leaves and stems
Edibility / Nutritional
- Young leaves and shoots
eaten raw in salads, or steam and boiled like spinach.
- Young stems popular as achara (native pickles) ingredient.
- Good sources of iron, calcium, vitamins B and C and amino acids.
- Tops are mildly laxative.
-The purplish variety used for diabetes because of assumed insulin-like
principle it contains.
- Juice used as emetic.
- Dried latex is purgative.
- Poultice of buds used for ringworm.
- Used as laxative and sedative; used for piles, nervous conditions, headache, insomnia.
- In Burma, the juice is employed as an emetic in cases of arsenical or opium poisoning.
- In Cambodia, used as poultice for fever with delirium; buds applied to ringworm.
- In Ayurveda, extracts
of leaves are used for jaundice and nervous debility.
- Juice used as emetic in opium and arsenic poisoning.
- In Sri Lanka, used for
liver disease, eye problems, constipation.
- Leaves used as food for gurami fish and pigs.
- Fodder for animals; use limited by laxative effect.
• Hypoglycemic / Anti-Diabetic:
Study evaluated the oral hypoglycemic activity of single and multiple doses of Ipomoea aquatica in healthy male Wistar rats after a glucose challenge. Results showed significant reduction in glucose concentrations in both single (33%, p<0027) and multiple (25%, p<00.02) doses. (1)
• Hypoglycemic / Comparable to Tolbutamide: An aqueous extract of the green leafy vegetable
Ipomoea aquatica is as effective as the oral hypoglycaemic drug tolbutamide
in reducing the blood sugar levels of Wistar rats. (3)
• Hypoglycemic / Glucose Absorption Inhibitory Effect: Inhibitory effect
of Ipomoea aquatica extracts on glucose absorption using a perfused
rat intestinal preparation: Study showed a significant inhibitory effect
on glucose absorption. Furthermore, results suggest the inhibition of
glucose absorption is not due to the acceleration of intestinal transit.
• Hypoglycemic / Oral Consumption Study showed the consumption of shredded, fresh, edible portion
of IA for one week, effectively reduced the fasting blood sugar of Streptozotocin-induced
diabetic rats. (5)
• Antioxidant / Antiproliferative: Antioxidant and antiproliferative activities of water
spinach (Ipomoea aquatica Forsk) constituents: Study showed the water
extract of stems had the highest antiproliferative activity. The ethanol
extract of the stems had the highest total phenolic compounds. The ethanol
extract of leaves had the highest amount of flavonoids. (2)
• Diuretic: Study on the diuretic activity of the methanol extract
of Ipomoea aquatica in Swiss albino mice showed good diuretic activity.
In all cases, the excretion of electrolytes and urine volume increase
was higher than the standard diuretic, furosemide. (7)
• Antioxidant: Study of a methanol extract yielded a compound ( 7-O-B-D-glucopyronosyl-dihydromquercetin-3-O-a-D-glucopyranoside)
that exhibited antioxidant activity with an EC50 value of 83 and showed
very strong lipid peroxidation-inhibitory activity in a liposome model
• Antimicrobial: Study investigating the antimicrobial efficacy of the leaf extract of three herbs – A longifolia, I aquatica and E fluctuans – on four pathogenic bacterial strains (E coli, P aeruginosa, S aureus and M luteus). Ipomoea aquatica exerted the higher amount of antimicrobial activity against the bacterial strains, better than the two other herb extracts. (9)
• Antiulcerogenic: Study in an aspirin-induced ulcer model in rats found Ipomoea aquatica to possess potent anti-ulcerogenic and ulcer-healing properties and can act as a potent therapeutic agent against peptic ulcer disease. (10)
• Cytotoxicity: Study isolated a purified bioactive compound from the leaf of Ipomoea aquatica – 7-O-B-D-glucopyranosyl-dihydroquercetin-3-O-a-D-glucopyranoside (DHQG). Results showed DHQG showed cytotoxicity towards cancer cell lines tested.
• Nootropic / Memory Enhancing Potential: Study suggests that MEIA markedly improves brain Ach level. MEIA treatment may be of value in reinforcing depressed cholinergic transmission in certain age related memory disorders and to improve memory and learning in normal individuals. (11)
• Anxiolytic: Study evaluated the anxiolytic activity of Ipomoea aquatica leaves. A methanol-ethanol extract significantly potentiated ketamine-induced sleep by reduction in latency to sleep and increased duration of sleep, suggesting the interaction of I. aquatica with CNS depressants. (12)
• Hypoglycemic/ Antioxidant: Study evaluated the hypoglycemic and antioxidant activity of methanolic extract of leaves in Swiss albino mice. Results showed potent hypoglycemic activity compared with control. Extract also showed potent free radical scavenging activity with vitamin C as standard. (14)
• CNS Depressant / Antiepileptic: Study on various animal models evaluated the CNS depressant and antiepileptic activities of a methanol extract of leaves of Ipomoea aquatica. Results showed dose-dependent and significant increases in onset to clonic and tonic convulsions or complete protection against seizures induced by strychnine and picrotoxin. There was also dose-dependent prolongation of pentobarbitone sleeping time and suppression of exploratory behavior. (15)
• Hepatoprotective / Thioacetamide-Induced Hepatotoxicity: Study evaluated the protective effects of ethanol extract of I. aquatica against liver damage induced by thioacetamine in rats. Results showed a protective effect in TAA-induced liver damage probably by contributing to its modulation on detoxification enzymes, antioxidant, and free radical scavenger effects. (17)
• Lead and Cadmium Content: Study was conducted to determine the concentrations of lead (Pb) and cadmium (Cd) in the top, middle, and bottom of edible portions of I. aquatica. Pb concentration showed a decreasing trend from the roots to the leaves, and from bottom to top section to shoot apex. The concentrations of Pb and Cd in the edible portions were far below the maximum tolerable daily intake for man set by the WHO. The bottom of the edible portion of the plant should be removed to minimize Pb intake. (13)
• Constituents and Pharmacological Potentiality: Some major plant compounds are: (1) Calystegines B1, a nortropane alkaloid, with potent inhibitory activity against rat lysosomal ß-glucosidase, (2) N‐cis-feruloyltyramine and N‐trans-feruloyltyramine, phenolic compounds isolated from the roots, considered potent inhibitors of prostaglandin synthesis, (3) 3α,7β-O-D-di glycopyranosyl-dihydroquercetin, a compound that has shown cytotoxicity against cancer cell lines viz. Hep-2 and A-549, and (4) Isochlorogenic acid a, b and c, phenolic compounds with collagenase inhibitory activity, antioxidant activity, anti-HIV activity. (19)
• Protective Against Cadmium-Induced Toxicity: Study evaluatd two aquatic vegetables, aqueous extracts of Ipomoea aquatica and Enhydra fluctuans, traditionally used against heavy metal toxicity in traditional medicine in India, for protective role against Cd-intoxication. Results suggest both extracts offered protection against Cd-induced toxicity by counteracting oxidative stress and ROS mediated apoptosis and/or promoting the elimination of Cd by chelating. (21)
• Toxicity Studies / Safety Profile / Leaves: Study evaluated the safety of an hydroalcoholic extract of Ipomoea aquatica Forsk. leaves in acute and sub-acute administration in a rodent model. Results showed no sign of toxicity during the study period—no change in general behavior, adverse effects and mortality. No significant changes were observed in organ weights and histopathological exam showed not morphological alterations. Results suggest a wide margin of safety for therapeutic use of the plant. (22)
• Antioxidant / Leaves: Ethanolic extract of leaves exhibited good antioxidant activity with IC50 values of 0.387 and 0.394 mg/mL against DPPH and ABTS radicals, respectively. Vitamin C content was 50 mg/100g and total phenolic content was 561 mg gallic acid equivalent per 100 g, both of which could be main contributors to the antioxidant capacity of the leaves. (see constituents above) (23)
• Nephroprotective / Gentamicin-Induced Toxicity / Leaves: Study evaluated the nephroprotective effect of water spinach ethanol extract of leaves on gentamicin-induced nephrotoxic rats. Results showed significant decrease (p<0.01) in the elevated serum creatinine and urea levels compared to gentamicin treated group. (24)