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Botany
Erect, branched and smooth
shrub, 1-3 meters high. Leaves are short-stalked, elliptic-lanceolate
to oblong-elliptic, 5-12 cms, narrowed at both ends, shining and short-stalked. Inflorescences
are axillary and terminal, peduncled, and have rather few flowers. Calyx is green, ovoid,
and short. Corolla is white, slender-tubed, 1.7 cm long; limb is 2 to
2.5 cm in diameter, composed of five, spreading, falcate, lanceolate
lobes. Follicles are red, oblong, 2-4 cm long, and longitudinally ridged.
Distribution
Common in thickets
at low altitudes.
Parts utilized
Leaves.
Uses
Folkloric
· Eczema: Boil
3 cups of chopped leaves in one gallon of water for 10 minutes; add
2 gallons of hot water.Also, fry the fresh leaves in oil and apply to
itchy skins lesions for symptomatic relief.
· Wound healing: Leaf juice.
· Hot Foot Baths: A local immersion bath covering the feet, ankles
and legs used for a variety of conditions: To relieve head, chest and
pelvic congestion; to stop nosebleeds; to relieve spasms and pains of
feet and legs; to induce sweating; to relieve menstrual cramps and headaches.
· Poulticed leaves applied on the abdomen to hasten childbirth.
· Erectile dysfunction: Recent use as "herbal viagra."
Boil 15-25 leaves in 3 glasses of water for
10 minutes; drink the decoction. (Note: Like
many of the herbal medicines touted as "herbal viagra," kampupot
use is rural folkloric with no known scientific or pharmacologic basis
for its claim.)
· Decoction of root and bark used for a varitety of stomach and
intestinal ailments.
· The white sap of the stem is applied to thorn injuries and
to hasten the surfacing of the thorn fragment.
· In Thailand, roots used to treat fevcer, pain and dysentery.
Studies
• Analgesic
/ Hypothermic: :
Voacangine was isolated from T pandacaqui which exhibited significant
analgesic and hypothermic effects in mice.
• Antiprotozoal: : In a study of 18 plants traditionally used in South Pacific archipelago Vanuatu, 15 plantsz showed strong cytotoxic effects specific for only one cancer line. T. pandacaqui leaves displayed activity against Trypanosoma cruzi.
• Anti-Inflammatory
/ Antipyretic / Antinociceptive: Study showed TP to
have significant antiinflammatory, antipyretic and antinociceptive activities
attributable to alkaloidal components.
• Hypotensive / Bradycardic:
(1) Cardiovascular activity of the crude alkaloidal fraction from Tabernaemontana
pandacaqui in the rat.: Study showed hypotensive and bradycardic
responses that might involve cholinergic, central mechanisms, biogenic
amines, acetylcholine and histamine.
(2) Intravenous injection of ethanol extracts of stem, leaf and flower exhibited a hypotensive activity not mediated through histaminic and muscarinic stimulation, a-adrenoceptor blockade or interference of sympathetic transmission.
• Neuropharmacological
/ CNS Depressant: Study of crude alkaloidal fraction from the stem of Tp suggested CNS depressant activity in rats and mice through reduction in spontaneous motility, potentiation of pentobarbital sleeping time and antinociception.
Caution
• Some reports of toxicity attributed to the milky
sap.
• Fruit reported to be highly poisonous, with its many seeds with
red fleshy covering.
Availability
Wild-crafted. |
