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Family Araceae
Pungapung
Amorphophallus paeoniifolius (Dennst.) Nicolson

CORPSE FLOWER
Chou mo yu

Scientific names  Common names 
Amorphophallus campanulatus Decne. Anto (Bis.) 
Amorphophallus chatty Andrews Apon (Tag.) 
Amorphophallus decurrens (Blanco) Kunth Apong-apong (Tag.) 
Amorphophallus dixenii K.Larsen & S.S.Larsen Bagang (Ibn.) 
Amorphophallus dubius Blume Bagong (Bik., Sul.) 
Amorphophallus giganteus Blume [Illegitimate] Balbag (Pal.)
Amorphophallus gigantiflorus Hayata Oroi (Bis.) 
Amorphophallus malaccensis Ridl. Pamangkilon (Bis.)
Amorphophallus microappendiculatus Engl. Pungapung (Tag.) 
Amorphophallus paeoniifolius (Dennst.) Nicolson Tigi (Pal.)
Amorphophallus rex Prain Tigi-nga-magmanto (Ilk.) 
Amorphophallus rex Prain ex Hook.f. Tokod-banua (Pamp.) 
Amorphophallus sativus Blume Corpse flower (Engl.)
Amorphophallus virosus N.E.Br. Elephant foot yam (Engl.)
Arum campanulatum Roxb. [Illegitimate] Leopard palm (Engl.)
Arum decurrens Blanco Stanley's washtub (Engl.)
Arum phalliferum Oken Whitespot giant arum (Engl.)
Arum rumphii Gaudich. [Illegitimate]  
Arum rumphii Oken  
Candarum rumphii Schott [Illegitimate]  
Conophallus sativus (Blume) Schott  
Dracontium paeonifolium Dennst.  
Dracontium polyphyllum G.Forst.  
Hydrosme gigantiflora (Hayata) S.S.Ying  
Kunda verrucosa Raf. [Illegitimate]  
Plesmonium nobile Schott  
Pythion campanulatum Mart.  
Amorphophallus paeoniifolius (Dennst.) Nicolson is an accepted name The Plant List

Other vernacular names
BENGALI: Olm Ole.
CHINESE: Xie bn yu, Nan xing tou, Nan yu, Ji zhao yu, Chou mo yu, You bang mo yu.
FIJIAN: Suran.
FRENCH: Gouniah d'Annam.
HINDI: Suran, Suranakanda, Jamikand, Jimmikand.
INDONESIAN: Suweg.
JAPANESE: Koniaku, Konjac, Konnyaku.
MALAYSIAN: Suran, Jimmikand.
NEPALESE: Ole.
POLISH: Dziwadlo.
SANSKRIT: Suranah.
TAMIL: Kizhangu.
THAI: Buk khang.
VIETNAMESE: Nua chuong.

Gen info
- In some countries, it has gained status as a cash crop due to high production potential, market acceptability, and good economic returns with productivity potential of 59-80 t/ha.

Botany
Pungapung is a perennial, stemless herb. Corm is depressed-globose, up to 30 centimeters in diameter, flowering before leafing every year from the previous year's corm. Stem-like structure, which bears the lamina, is merely the petiole, 1 meter or more high, radically developed from the corm. Leaves are usually solitary, the blades up to 1 meter in diameter, trisected, the segments dichotomous, the ultimate ones pinnately divided into oblong to oblong-obovate, acuminate lobes. Spathe is sessile, broadly campanulate, dull-purplish, the margins somewhat spreading or recurved, waved and crenulate, up to 30 centimeters in diameter. Spadix (a spike of flowers contained in the spathe) is hardly longer than the spathe, the appendage ovoid, variously sulcate or depressed, up to 15 centimeters long, are malodorous when flowering.

Distribution
- Common in most or all, provinces of Luzon and in Mindoro, in thickets and secondary forests, along roads, trails, etc., at low and medium altitudes in settled areas.
- Occurs in India through Malaya to Polynesia.

Constituents
Corm analysis: 74% moisture; 0.73% ash; 5.1% protein; 18% carbohydrate, 0.61% crude fiber, giving 1,000 calories per kilo. In food value, comparable to kalabasa, superior to sinkamas. •
Yields amblyone, a tritepenoid with antibacterial and cytotoxic activities.
Phytochemical screening of various tuber extracts yielded alkaloids, carbohydrates, coumarins, steroids, saponins.
Tubers yielded an active diastatic enzyme- amylase, betulinic acid, B-sitosterol, stigmasterol, B-sitosterol palmitate, lupeol, triacontane, amino acids, carbohydrates, saponin, thiamine, riboflavin, niacin and carotene.
Study evaluated methanol (ME) and 70% hydroalcoholic (AE) extracts of tubers for flavonoidal and total phenolic content. Flavonoidal content was 46.33 mg/g (ME) and 36.88 mg/g (AC). Total phenolic content were 12.67 mg/g (ME) and 6.25 mg/g (AE). (
24)
• Major nutrient and constituent analysis of corm suggests a good source of energy, sugar, starch, proteins and minerals, with average nutritional profile of starch 11-28%, sugar 0.7-1.7%, protein 0.8-2.6%, fat 0.07-0.40%, mean energy value 236-566.7 Kj/100g. Ranges of macro minerals and soluble oxalates from different varieties in mg/100g were: K 230-417, P 129-247, Ca 131-247, Fe 1.97-5.56, Mn 0.19-0.65, Zn 1.12-1,92m soluble oxalate 6.65- 18.50. The mean soluble oxalate content of 13.53 mg/100g was safe from the viewpoint of urinary oxalate accumulation that may lead to kidney stones.  (38)
 
- Phytochemical analysis of methanol, ethanol, ethyl acetate, and aqueous extracts of tubers yielded polysterols, phenols, flavonoids, tannins, terpenoids steroids, gum and mucilage, carbohydrates. Saponins were present only in the methanol and aqueous extracts. None yielded alkaloids. (see study below) (45)    

Graphic >
Spathe prior to malodorous flowering stage.

Properties
- Flower odor has been described as "evil", similar to decaying meat; hence, its well-deserved name "corpse flower." (see study below) (55)
- Corms are caustic, stomachic and tonic.
- Corms considered acrid, astringent, thermogenic, irritant, anodyne, anti-inflammatory, anti-hemorrhoidal, haemostatic, expectorant, car
- Raphide crystals on the corm, petiole and leaves produce irritation upon contact with the skin.

- Tubers are considered appetizer, antibacterial, antifungal, anodyne, aphrodisiac, anti-inflammatory, antihemorrhoidal, cytotoxic, emmenagogue, hemostatic, expectorant, carminative, digestive, stomachic, anthelmintic, liver tonic, rejuvenating and tonic.
- Studies have suggested antibacterial, cytotoxic, antioxidant, hepatoprotective, analgesic, immunomodulatory, anthelmintic, anticancer, anticonvulsant, antidepressant, chemopreventive, gastroprotective, antidiarrheal, antihyperglycemic, antineuropathic properties.

Parts utilized
Corm, roots, leaves.

Uses
Edibility / Nutrition
• Leaves and roots.
• Good source of protein and starch.
• A vegetable in various ethnic cuisines.
• Rhizomes
preferably cooked, acrid when raw. May cause perioral burning and itching.
Petioles of young unexpanded leaves are edible when thoroughly cooked.
In time of scarcity, corms are sometimes eaten. Corms provides about 1,000 calories per kilo; comparable in food value to kalabasa, superior to singkamas.
In India, corms used in curries and pickles.
Folkloric
• Poultices of corm are antirheumatic. Also used for hemorrhoids.
• Plants used for cough.
• Roots are used for boils and hemorrhoids.
• Tubers are also used for hemorrhoids.
• In India, corm is considered stomachic and tonic; used in piles and given as restorative in dyspepsia and debility. Tuberous roots are used for treatment of piles, abdominal pains, tumors, spleen enlargement, asthma and rheumatism. Also, corms used as restorative in dyspepsia, debility, etc. Roots used for boils and ophthalmia; also as an emmenagogue. Petioles used in scorpion bites and dysmenorrhea. Tubers also used for post delivery problems, migraine, and neck swelling.
• In Ayurveda, traditionally used in arthralgia, elephantiasis, tumors, inflammations, hemorrhoids, hemorrhages, vomiting, cough, bronchitis, asthma, dyspepsia, colic, constipation, hepato-splenopathies, amenorrhea, dysmenorrhea, seminal weakness, fatigue and general debility.
• In Unani medicine, given as vegetable in sluggish liver.
• Corms applied externally to relive the pain of rheumatic swellings.
When fresh, acts as acrid stimulant and expectorant.
- In Kerala, India, dried and powdered corm mixed with curd and hot water, and drunk for treatment of jaundice by the kurichia, adiya, and kuruma tribes in Wayand. Cooked corm with curd used for treatment of hemorrhoids. Leaf and stem juice used for treatment of ulcers. (54)
Others

Feed: Leaves and corms are common feed for hogs.

Studies
Antibacterial / Cytotoxic / Amblyone:
Amblyone, a triterpenoid isolated from A campanulatus showed to have good antibacterial activity and moderate cytotoxic activity. (1)
Antibacterial / 3,5-diacetylambulin:
3,5-diacetylambulin, a flavonoid isolated from A. campanulatus showed antibacterial activities against 4 gram positive and 6 gram-negative bacterial. (6)
Hepatoprotective / CCl4-Induced Damage / Antioxidant:
Study on ethanolic and aqueous extracts of Amorphophallus campanulatus showed antioxidant activity. Results showed potent hepatoprotective action against carbon tetrachloride-induced hepatic damage. The possible mechanism of antioxidant activity may be due to the free radical scavenging potential from the flavonoids in the extracts. (2)
Hepatoprotective / Acetaminophen-Induced Damage Study of dried tuber on acetaminophen-induced hepatic injury in albino rats showed increase in levels of superoxide dismutase (DOS), catalase (CAT) and glutathione peroxidase (GPx) suggesting hepatoprotective and antioxidant properties.
Analgesic / Tubers:
Study in mice was done on a methanol extract of A campanulatus tuber for in-vivo analgesic activity using a tail flick and acetic acid induced writhing methods. Results showed significant dose-dependent analgesic activity. Effect might be due to plant phytoconstituents which inhibit cyclooxygenase enzyme or through an effect on central opioid receptors (µ-receptors). (3)
Immunomodulatory:
Study of a methanol extract of AC tuber on immunological function in mice exhibited immunomodulatory activity by causing a decrease in charcoal clearance, spleen index and delayed-type hypersensitivity (DTH) response. (7)
Phytochemicals / Anthelmintic:
Corms yielded steroids, alkaloids, tannins, glycosides, carbohydrates, phenols, flavonoids, saponins, starch and proteins. Results showed the corm chloroform and methanol extracts and crude tannins showed good anthelmintic activity close to the standard drug albendazole. (8)
CNS Depressant Activity / Acute Toxicity Study / Tuber: Study showed a dose-dependent decrease in CNS activity with sedation and decrease in locomotor activity of the experimenting animal. Acute toxicity studies showed mortality at 2500 mg/kg body weight. Results suggest that petroleum ether extract can be safely used up to dose of 1500 mg/ kg body weight. (9)
Antioxidant / Tubers: Study evaluated the antioxidant activity of a methanolic and aqueous extract of tubers for free radical scavenging property on DPPH, NO, and reducing power assays. Results showed the aqueous extract with more antioxidant activity compared to the methanolic extract. (13) Study evaluated the in-vitro antioxidant activity of various solvent extracts of A. paeoniifolius tubers. A methanol extract of AP tuber showed maximum in-vitro antioxidant activity in comparison to other solvent extracts which may be attributed to its higher phenolic content. (41)
Hepatoprotective in Paracetamol-Induced Liver Damage: Study of methanol and aqueous extracts of tubers in paracetamol-induced liver damage in rats showed hepatoprotective activity. There was significant reduction of hepatic enzyme values, almost comparable to silymarin. The hepatoprotective activity was confirmed by histopathologic examination of control and treated animals. (
14)
Cytotoxicity / Anticancer Potential: Study evaluated the cytotoxic property of different solvents of A. paeoniifolius tuber using Allium cepa root tip cells and HEp-2 cell line invitro models. Results exhibited cytotoxic activity, predominant in the petroleum ether and ethanolic extracts with dose-dependent antiproliferative activity on HEp2 cells. (15)
Antioxidant Against Thioacetamide-Induced Oxidative Stress: Study evaluated the protective effect of extracts against thioacetamide-induced oxidative stress in rats. Silymarin was used as control. Results showed a methanolic extract to have higher antioxidant and radical scavenging activity than an n-hexane extract, attributed to higher phenolic and flavonoid content. There was histopathological support for the dose-dependent effects. (16)
Anticonvulsant: Study evaluated petroleum ether extracts of A. paeoniifolius for anticonvulsant activity. Diazepam was used as standard drug. Results showed dose-dependent activity regarding onset of convulsion. (18)
Cytotoxic / Apoptotic / Tubers / Human Colon Carcinoma Cell Line: Study evaluated dose-dependent cytotoxic and apoptosis inducing effects of sub fractions of methanolic extract of tubers on colon cancer cell line, HCT-15. Among the subfractions, the chloroform fraction showed potent cytotoxic and apoptotic activity. Results suggest the fractions dose-dependently suppress proliferation of HCT-15 cells by inducing apoptosis. (
20)
Antioxidant / Protective Against H2O2 Induced Oxidative Damage: Study evaluated tuber extracts against H2O2 induced oxidative damage in human erythrocytes and leucocytes. Results showed benefits of the tuber extracts in preventing H2O2 oxidative human RBC damage and improving RBC membrane permanence. The methanol extract was more effective than others. (
21)
Chemopreventive / Tuber / Induced Colon Carcinogenesis: Study evaluated a tuber methanolic extract on aberrant crypt foci (ACF) formation, colonic cell proliferation, lipid peroxidation damage and antioxidant status in a long term preclinical model of DMH-induced colon carcinogenesis in rats. Results showed significant chemopreventive effect. (
22)
Synergistic Depressant Activity with Diazepam: Study of a petroleum ether extract was found to have CNS depressant activity. A significant synergistic effect of the PE extract with diazepam was found, with little synergistic effect with phenobarbitone. PE extract components may bind with the α subunit and facilitate the GABA mediated Cl- channel opening causing cell hyperpolarization and CNS depressant action. (
23)
Gastroprotective / Corms: Study evaluated the gastroprotective activity of a methanolic extract of corms against pylorus ligation induced gastrotoxicity in albino rats. Results showed significant dose dependent reduction in the elevated gastric parameters with significant restoration of protective GSH levels and suppression of LPO levels in tissues. Lansoprazole was used as standard. The activity may be due to the polyphenolic compounds known to possess anti-ulcer activity. (
24)
• Oral Toxicity Evaluation / Tuber: Study evaluated acute and subacute oral toxicity studies of methanolic and aqueous extracts of A. paeoniifolius tuber in Swiss albino mice. In acute toxicity testing with single 2000 mg/kg dose of the extracts, there was not treatment related mortality and morbidity in any group. In subacute testing withe repeated dose of 1000 mg/kg daily for 28 days, there were not significant changes in behavior, body weight, hematologic and histological parameters, and no treatment related mortality or morbidity with doses used. (26)
• Underutilized Crop / Synopsis: Synopsis reports on Amorphophallus paeoniifolius as an underutilized crop with remarkable nutritional quality and potential as a valuable food source for human consumption. Despite its economic potential as food material, there is very limited scientific information on post-harvest characteristics and marketing potential. The research evaluates and assesses the complete utilization of A. paeoniifolius and its potential in the food industry. (27)
• Gastrokinetic Activity / Tubers: Study evaluated the effect of Amorphophallus paeoniifolius tuber on gastrointestinal motor functions. Pretreatment of extracts significantly increased the number of feces, wet and dry weight of feces, moisture content, gastric emptying and intestinal transit. Results were comparable to metoclopramide. The aqueous and methanol extracts also showed contraction of fundus and ileum in isolated preparations. Extracts yielded fair amounts of glucomannan, total phenolics and flavonoids. The gastrokinetic potential of the tuber extracts may be attributed to glucomannan and betulinic acid in the extracts. (28)
• Antidiarrheal / Leaves: Study evaluated the anti-diarrheal activity of A. paeoniifolius leaves in a castor oil-induced diarrhea model in Swiss albino mice. At doses of 100, 200, and 400 mg/kg, there was a statistically significant (p<0.05) dose dependent reduction of total number of diarrheic feces. (29)
• Antioxidant / Tuber: Study evaluated the antioxidative and radical scavenging potential of a tuber extract of A. paeoniifolius. The extract showed a maximum of 68.6% of DPPH scavenging activity and maximum inhibition of 74% and 67.2% in ABTS and H2O2, respectively. The antioxidant efficiency and inhibition of oxidation was found to be dose-dependent. HPTLC profile of the extract yielded the presence of polyphenols such as gallic acid, resveratrol, quercetin, and two unidentified compounds. (3
0)
• Diabetic Neuropathy / Tubers: Study evaluated the effect of methanolic extract of tubers of Amorphophallus paeoniifolius in the treatment of diabetic neuropathy in STZ-induced diabetic rats using tail flick test, swim endurance test, and tota-road methods. Results showed significant improvement in the measured parameters compared to negative control group and suggest potential use in the management of diabetic neuropathy. (31)
• Population Structure / Potential for Breeding for Global Acceptance: Corms and leaves of elephant foot yams are important foods in the local diet of many Asian regions. The crop has high agroecological adaptation and suitability for agroforestry system. Study suggests regional action should be incorporated in genetic conservation and breeding efforts to develop new varieties with global acceptance. (32)
• Combined Effect of Vigna radiata and A. paeoniifolius / Lipid Lowering Potential and Antiatherogenic Effect: Study evaluated the combined effect of Mung bean (V. radiata) and elephant foot yam (A. paeoniifolius) on serum lipids and atherogenic indices in albino rats and compared it with standard drug Cholestyramine. Results showed lowering of total cholesterol, triglycerides, LDL and VLDL (p<0.01) along with a significant increase (p<0.01) in HDL in rats. The combination of powdered sprouted mung bean and yam powder showed excellent lipid lowering potential and reduced atherogenic indices. (33)
• Antihyperglycemic / Antinociceptive / Corms: Study evaluated the antihyperglycemic and antinociceptive potential of methanol extract of A. campanulatus corms in Swiss albino mice. At highest dose level using oral glucose tolerance tests in glucose loaded mice, results showed a near equivalent antihyperglycemic potency as that of glibenclamide. In acetic acid induced pain model in mice, the extract, even at lowest dose, was more potent than the lower dose of aspirin. (34)
• Beneficial Effect on Experimental Ulcerative Colitis / Tuber: Study evaluated the effects of tuber extracts of A. paeoniifolius on acetic acid induced ulcerative colitis in Wistar rats compared to standard drug prednisolone. (35)
• Antihyperlipidemic / Tuber: Study evaluated the antihyperlipidemic activity of amorphophallus paeoniifolius tuber in Triton WR-1339 induced hyperlipidemic rats. Tubers contained high concentration of total phenols which possess strong anti-hyperlipidemic activity. Results showed significant decrease in serum cholesterol, triglycerides, LDL, and VLDL along with a significant increase in HDL. Results suggest a potential protective role in coronary heart disease. (36)
• Curative Effect on Experimental Hemorrhoids / Tuber: Study evaluated the effect of methanolic and aqueous extract of A. paeoniifolius tuber on hemorrhoids in rats induced by croton oil applied in the ano-rectal region. Results showed aqueous extract showed more pronounced effect than methanolic extract. Effect was attributed to antioxidant and anti-inflammatory properties. Results validate its ethnomedicinal use of tuber in hemorrhoids. (37)
• Hepatoprotective Secondary Metabolite / Flavonoid Quercetin / Corm: Study isolated the flavonoid from an ethyl acetate fraction of corm and screened for hepatoprotective activity on CCl4-induced model. Results showed significant reduction of elevated enzymes, increased protein level, and attenuation of damaged hepatocytes toward normal texture. (39)
• Extract Syrup Formula as Nutritive Antioxidant Drink: Extract of elephant foot yam (EFY) contains a antioxidant flavonoid compound that has potential to be utilized as functional food beverage. Study evaluated the antioxidant activity, pH value, viscosity and sensory properties of EFY extract syrup with various extract formulas. Results showed variations in extract concentration in the formula have effects on the measured properties. Syrup with 4% extract concentration (F3) exhibited favorable properties with highest antioxidant activity (71.39 ppm), pH 4.97, 0.265 c. viscosity. In terms of consumer preference, syrup with 0.6% extract (F1) is most preferable in color, flavor, and aroma. Study suggests potential as an antioxidant source as syrup added to healthy drink. (40)
• Laxative Effect / Glucomannan and Betulinic Acid / Tuber: Study evaluated the effect of tubers of A. paeoniifolius and its active constituents on experimentally induced constipation. Isolated phytoconstituents by FT-IR, NMR, and MS were identified as betulinic acid and ß-sitosterol. Constipation was induced by loperamide. Treatment with tuber extracts, glucomannan and betulinic acid showed significant (p<0.05) increase in fecal parameters and intestinal transit in constipated rats. Effects were comparable to laxative drug, sodium picosulfate. The principal constituents, glucomannan and betulinic acid may have played an important role in relieving the constipation. (42)
• Anticancer / Breast Cancer Cell Lines / Tuber: Study evaluated the anticancer efficacy of extract of A. paeoniifolius tuber against estrogen positive MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. The extract showed significant cytotoxic activity in both cancer cell lines in a dose- and time-dependent manner. The extract significantly reduced migration in both cell lines while the effect on inhibition of adhesion and invasion was higher in MDA-MB-231 cells. Staining suggested that the extract induced apoptosis in the cells which was further validated by attenuation of antiapoptotic Bcl-2 and induction of pro-apoptotic Bax, Caspase-7 expression and cleavage of PARP. (43)
• Silver Nanoparticles / Antibacterial / Leaves: Study reports on a one-step, eco-friendly green synthesis of AgNPs using a leaf extract of A. paeoniifolius as reducing agent. The synthesized AgNPs showed potential antibacterial activity against both gram positive and gram negative bacteria. (44)
• Antibacterial / Tubers: Study evaluated ethyl acetate, methanol,aqueous, and ethanol extracts of A. paeoniifolius for activity against human bacterial pathogens using agar-well diffusion assay. The ethyl acetate extract showed maximum activity for Bacillus subtilis (7.5mmZOI) and Staphylococcus aureus (7mmZOI). (see constituents above) (45)
• Diabetic Effect / Beneficial or Detrimental / Review: There have been concerns on elephant foot yam tubers being detrimental for diabetic patients. A literature review showed the tuber to be a good source of carbohydrates, protein, fiber, and minerals but low in fat. Secondary metabolites of the tuber have significant anti-hyperglycemic effect. Study concludes the elephant foot yam tuber is safe and beneficial for patients with diabetes. (46)
• Amblyone / Anticancer: Study evaluated the anticancer activity of Amblyone, a phytochemical from the tuber of elephant foot yam and compared its activity with commonly used antiapoptotic drug Tetrahydro-isoquinoline amide substituted phenyl pyrazole derivative. In silico analysis showed a docking score of -12.2 kcal/mol for amblyone compared with 7.7 kcal/mol for the tetrahydroisoquinoline amide substituted phenyl pyrazole derivative. The better docking score indicates that amblyone can bind firmly on the groove of Bcl-2 protein which regulates activity of pro-apoptotic proteins by direct binding and sequestration. (47)
• Antibacterial / Tuber and Peel Extracts: Study evaluated the antibacterial activity of ethanol extract of tuber and peel of Amorphophallus paeoniifolius. The ethanolic tuber extract showed inhibitory effect on four bacterial species viz. S. aureus, P. aeruginosa, E. coli, and S. mutans, with diameter of ZOI ranging from 6mm-18mm. The ethanolic extract of peel showed inhibitory effect only on two bacterial species, S. aureus and P. aeruginosa. The water extract of peel and tuber inhibited only one species each, S. mutans and S. aureus, respectively. (48)
Antihyperlipidemic / Stem: Study evaluated the antihyperlipidemic efficacy of stem powder of Amorphophallus paeoniifolius in lowering elevated serum lipids in adult male albino rats. Triton-X-100 increased the total cholesterol, reduced HDL level and atherogenic index. Treatment reduced total cholesterol, increased HDL, reduced both weight and AI index. (49)
• Antidiabetic / A. paeoniifolius and Borassus flabellifer: There have been concerns among diabetic patients that the use of germinated endosperm of sugar palm (GESP-Borassus flabellifer) and elephant foot yam tuber (EFYT) will further deteriorate existing hyperglycemia. Study evaluated the effect of supplementary feeding of powder of GESP, EFYT, and their mixture in addition to regular diet in alloxan induced diabetic rats. Results showed the foodstuffs significantly (p<0.001) reduced FBG. The mixture of GESP and EFYT showed maximum antidiabetic effects followed by GESP and EFYT, respectively. Study suggests the foodstuffs may restore damaged pancreatic ß-cell functions. Nutrient contents like fiber, zinc, and antidiabetogenic phytochemicals in the foodstuffs could contribute to these effects. (50)
Peroxidase Source / Corms: Peroxidases have wide applications viz. chemical synthesis, medicine, food industry, bioremediation of wastewater, biosensing, and biotechnology. Elephant foot yam (EFY) is an attractive source of enzymes. Study evaluated the peroxidases from corms of elephant foot yam, roots of Daucus carota (carrot), and Aramoracia rusticana (horseradish).
Elephant yam corm peroxidase (ECP) demonstrated 4.5 times higher specific gravity compared with carrot root peroxidase (CRP(. ECP showed retention of high activity over a broad pH range and higher temperature optima and thermal stability compared to CRP and horseradish peroxidases. Peroxidases are used for bioremediation of wastewater contaminated with hazardous aromatic compounds along with Cd, Pb, and toxic compounds like sodium azide. Results suggest elephant foot yam can be used as a rich and convenient source of peroxidase. (51)
• Anti-Inflammatory / Mechanism / Tubers: Study evaluated the anti-inflammatory activity of various extracts of dried and powdered tubers using carrageenan induced paw edema model in rats. Results showed only the methanol extract showed prominent anti-inflammatory activity. The ME also showed anti-histaminic effect. (52)
• Mutagenicity / Corm: Study evaluated the toxicity of A. paeoniifolius corm extracts to Allium cepa chromosomes. Results showed that as corm concentration increases, the number of root germination of A. cepa decreases. Interestingly, the mitotic index also decreased while chromosomal aberrations increased. Prominent chromosomal aberrations in treated samples were laggards, vagrant chromosomes, bridge with fragments, sticky chromosomes, disoriented chromosomes, and chromosomal breakage. The study may be the first evidence of mutagenicity and root growth inhibition of A. paeoniifolium corm extracts to A. cepa.   (53)
• Inflorescence Odors: The chemical composition of inflorescence odors of 80 species of Amorphophallus (Araceae) were determined by headspace-thermal desorption GC-MS. Dimethyl oligosulphides were found as common constituents of Amorphophallus odours and were the most abundant components in almost half of the species studied. Species producing 1- and 2-phenylethanoids cluster in two unrelated clades. Some species with gaseous odors were found closely related to species producing odors more reminiscent of rotting meat in which the dominant dimethyl oligosulphides were accompanied by various minor components. Rotting meat odors are usually found in species of darker inflorescences. Some have pleasant odors, from fruity to anise-like, Presence of pollinator resource has been a factor in influencing the evolution of odors in Amorphophallus. (55)
• Potential Biopesticide / Increased Shelf Life of Stored Food Grains: Food grain losses due to insect infestation during storages is a serious problem. Bioactive flavonoids from EFY against α-amylase were isolated. The acetone extract yielded the highest flavonoid content of about 544.8 µg quercetin equivalent/g compared to other extracts. The AE also yielded lesser α-amylase activity (30.836 IU) which signifies a-amylase inhibition. Flavonoid constituent, 9,12-octadecadienoic acid showed highest peak in GC-MS analysis of the AE. Whole grains and moong dal treated with the AE of 0.25% concentration was 100% efficient in repelling S. oryzae and T. castaneum from wheat and moong dal (p<0.001) with flour disc bioassay FDI-90.47%. Results suggest potential as a biopesticide against insects that infest stored food grains and thereby increase shelf life and restore nutritional value of grains. (56)
• Gastrokinetic Effects / Tuber: Study evaluated the effect of A. paeoniifolius tuber on gastrointestinal motor functions. Metochlopramide was used as reference prokinetic drug. Isolated tissue preparations were used to check the effect of the extracts on fundus and intestinal contractility. Pre-treatment with extracts significantly increased the number of feces, wet and dry weight of feces, moisture content, gastric emptying and intestinal transit. Results were comparable to MET. Methanol and aqueous extracts showed contraction of fundus and ileum in isolated preparations. The gastrokinetic potential of the tuber extracts may be attributed to the presence of glucomannan and betulinic acid. (57)

Availability
Wild-crafted.
Capsules, supplements in the cybermarket.


Updated March 2021 / March 2018 / December 2016


PHOTOS / ILLUSTRATIONS
Photos © Godofredo Stuart / StuartXchange

Additional Sources and Suggested Readings
(1)
Antibacterial, antifungal and cytotoxic activities of amblyone isolated from Amorphophallus campanulatus
Alam Khan, Moizur Rahman, MS Islam / 2008. vol 40. issue 1.pp 41-44
(2)
HEPATOPROTACTIVE ACTIVITY OF AMORPHOPHALLUS CAMPANULATUS CORM ON CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN RATS / Kaushik B.*, Nandanae S., Gendle R., Patel R., Verma L., Verma S. , 13th APTI Convention , 02/10/08, GGDU, Bilaspur, CG, (2008)
(3)
Analgesic activity of Amorphophallus campanulatus tuber
/ J A Shilpi et al / Fitoterapia
Volume 76, Issues 3-4, June 2005, Pages 367-369 / doi:10.1016/j.fitote.2005.03.024
(4)
ANTIOXIDANT AND HEPATOPROTECTIVE ACTIVITY OF ETHANOLIC AND AQUEOUS EXTRACTS OF AMORPHOPHALLUS CAMPANULATUS ROXB. TUBERS / Sanjay Jain et al / Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 66 No. 4 pp. 423 - 428, 2009
(5)
HEPATOPROTECTIVE AND ANTIOXIDANT EFFECTS OF AMORPHOPHALLUS CAMPANULATUS
AGAINST ACETAMINOPHENINDUCED HEPATOTOXICITY IN RATS
/ Surendhra Kumar Singh, N Rajasekar et al / International Journal of Pharmacy and Pharmaceutical Sciences, Vol 3, Issue 2, 2011
(6)
Antibacterial, antifungal and cytotoxic activities of 3,5- diacetyltambulin isolated from Amorphophallus campanulatus Blume ex. Decne / Khan A, Rahman M, Islam MS / DARU Vol. 16, No. 4 2008
/ DARU Vol. 16, No. 4 2008
(7)
Immunomodulatory Activity of the Methanol Extract of Amorphophallus campanulatus (Araceae) Tuber
/ A S Tripathi, V Chitra, N W Sheikh et al / Tropical Journal of Pharmaceutical Research October 2010; 9 (5): 451-454
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PHYTO CHEMICAL AND ANTHELMINTIC EVALUATION OF CORM OF AMORPHOPHALLUS CAMPANULATUS / R Ramalingam, K Hima Bindu et al / International Journal of Pharma and Bio Sciences V1(2)2010
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Effects of Petroleum Ether Extract of Amorphophallus paeoniifolius Tuber on Central Nervous System in Mice / S S Das, Malini Sen, Y N Dey et al / Indian J Pharm Sci. 2009 Nov–Dec; 71(6): 651–655.
doi: 10.4103/0250-474X.59547

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Amorphophallus paeoniifolius (Dennst.) Nicolson / Chinese names / Catalogue of Life, China
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Sorting Amorphophallus names / Authorised by Prof. Snow Barlow / Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1997 - 2000 The University of Melbourne.
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Phytochemical investigation of extract of Amorphophallus campanulatus tubers / Seema Firdouse*, Parwez Alam /
International Journal of Phytomedicine 3 (2011) 32-35
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EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY OF AMORPHOPHALLUS CAMPANULATUS (ROXB.) EX BLUME DECNE / K. G. SAHU∗, S. S. KHADABADI and S. S. BHIDE / Int. J. Chem. Sci.: 7(3), 2009, 1553-1562
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Hepatoprotective activity of Amorphophallus paeoniifolius tubers against paracetamol-induced liver damage in rats / Pramod J Hurkadale*, Pournima A Shelar, Siddhalingesh G Palled, Yuvaraj D Mandavkar, Ajay S Khedkar / Asian Pacific Journal of Tropical Biomedicine (2012)S238-S242
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Cytotoxic Activity of Amorphophallus paeoniifolius Tuber Extracts in vitro / J. Angayarkanni, K M Ramkumar, T Poornima and U Priyadarshini / American-Eurasian J. Agric. & Environ. Sci., 2(4): 395-398, 2007.
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Protective effect of Amorphophallus campanulatus (Roxb.) Blume. tuber against thioacetamide induced oxidative stress in rats / Puthuparampil Nazarudeen Ansil, Anand Nitha, Santhibhavan Prabhakaran Prabha, Pallara Janardhanan Wills, Vahab Jazaira, Mukalel Sankunni Latha* / Asian Pacific Journal of Tropical Medicine (2011)870-877 / doi:10.1016/S1995-7645(11)60211-3
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EVALUATION OF ANALGESIC ACTIVITY OF METHANOLIC EXTRACT OF AMORPHOPHALLUS PAEONIIFOLIUS TUBER BY TAIL FLICK AND ACETIC ACID-INDUCED WRITHING RESPONSE METHOD / YADU NANDAN DEY, SHANKHAJIT DE AND AJOY KUMAR GHOSH* / International Journal of Pharma and Bio Sciences, Vol.1/Issue-4/Oct-Dec.2010
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Effects of the petroleum ether extract of Amorphophallus paeoniifolius on experimentally induced convulsion in mice / Shankhajit De, Yadu Nandan Dey, Sudesh Gaidhani, Sarada Ota / International Journal of Nutrition, Pharmacology, Neurological Diseases, 2012, Vol 2, No 2, pp 132-134. / DOI: 10.4103/2231-0738.95971
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A phytopharmacological review on an important medicinal plant - Amorphophallus paeoniifolius / Yadu Nandan Dey, Sarada Ota, N. Srikanth, Mahvish Jamal, and Manish Wanjari / Ayu. 2012. Jan-Mar, 33(1): 27-32 /doi: 10.4103/0974-8520.100303
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Cytotoxic and apoptotic activities of Amorphophallus campanulatus (Roxb.) Bl. tuber extracts against human colon carcinoma cell line HCT-15 / P.N. Ansil, P.J. Wills, R. Varun, M.S. Latha / Saudi Journal of Biological / DOI: 10.1016/j.sjbs.2014.01.004
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Protective effect of Amorphophallus campanulatus tuber extracts against H 2 O 2 induced oxidative damage in human erythrocytes and leucocytes / Souravh S Bais, Prashant Y Mali / IJGP, 2013, Vol 7, Issue 2: pp 111-116.
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Chemopreventive effect of Amorphophallus campanulatus (Roxb.) blume tuber against aberrant crypt foci and cell proliferation in 1, 2-dimethylhydrazine induced colon carcinogenesis. / Ansil PN, Prabha SP, Nitha A, Latha MS / Asian Pacific journal of cancer prevention : APJCP 14:9 2013 pg 5331-9
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Synergistic depressant activity of Amorphophallus paeoniifolius in Swiss albino mice
/ Yadu Nandan Dey, Shankhajit De, Ajoy Kumar Ghosh, Sudesh Gaidhani, Suman Kumari, Mahvish Jamal /. Journal of Pharmacology & Pharmacotherapeutics, 2011; Volume 2, Issue 2: pp 121-123 / PMID: 21772777 /
DOI: 10.4102/0976-500X.81910
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Invitro Quantification of Flavonoids and Phenolic content of – Suran / H.N.Nataraj*, R.L.N.Murthy and Dr.S. Ramachandra Setty / Int.J. ChemTech Res.2009,1(4)
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Amorphophallus paeoniifolius / Synonyms / The Plant List
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Oral toxicity of Amorphophallus paeoniifolius tuber / Yadu Nandan Dey, Manish M. Wanjari*, Dharmendra Kumar, Vinay Lomash, Sudesh N. Gaidhani, Ankush D. Jadhav / J Pharm Pharmacogn Res 2017; 5(1): pp 55-68 / ISSN: 0719-4250
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PHYTOCONSTITUENT CHARACTERIZATION AND APPLICATION OF Amorphophallus paeoniifolius IN DEVELOPMENT OF FOOD PRODUCTS / ANURADHA SINGH / Synopsis submitted in fulfillment of the requirements for the Degree of Doctor of Philosophy
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Gastrokinetic Activity of Amorphophallus paeoniifolius Tuber in Rats / Yadu Nandan Dey, Shivani Mahor, Dharmendra Kumar, Manish Wanjari, Ankush Jadhav / Journal of Intercultural Ethnopharmacology. 2016;5(1)36-42 / DOI 10.5455/jice.20151211063819
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STUDIES ON ANTIDIARRHOEAL ACTIVITY OF LEAVES OF AMORPHOPHALLUS PAEONIIFOLIUS IN EXPERIMENTAL ANIMALS / Purwal, V. Shrivastava and U. K. Jain* / INTERNATIONAL JOURNAL OF
PHARMACEUTICAL SCIENCES AND RESEARCH, 2011; 2(2): pp 468-471 / ISSN: 0975-8232 /
DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.
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Antioxidant potential of Amorphophallus paeoniifolius in relation to their phenolic content
/ Jayaraman Angayarkanni, Kunga Mohan Ramkumar, Ulaganathan Privadharshini & Poornima Ravendran / Pharmaceutical Biology, Vol 48, Issue 6 (2010) / https://doi.org/10.3109/13880200903241846
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Beneficial effect of Amorphophallus paeoniifolius in the management of diabetic neuropathy / D S Mohale and A V Chandewar / 23rd International Conference on Herbal and Alternative Remedies for Diabetes and Endocrine Disorders, November 02-04, 2017 Bangkok, Thailand / DOI: 10.4172/2155-6156-C1-073
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Population structure of elephant foot yams (Amorphophallus paeoniifolius (Dennst.) Nicolson) in Asia / Edi Santosa, Chun Lan Lian, Nobuo Sugiyama, Raj Shekhar Misra, Patchareeya Boonkorkaew, Kanokwan Thanomchit / PLOSone, 12(6): e0180000 / https://doi. org/10.1371/journal.pone.0180000
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Combined efficacy of Vigna radiata (L.) R. Wilczek and Amorphophallus paeoniifolius(Dennst.) Nicolson on serum lipids in albino rats / P B Benil, R Lekshimi, N Viswanathan, E Jollykutty, R Rajaakrishnan, J Thomas, A H Alfarhan / Saudi Journal of Biological Sciences, Vol 24, Issue 6, Sept 2017: pp 1249-1254 / https://doi.org/10.1016/j.sjbs.2017.03.003
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A PRELIMINARY ANTIHYPERGLYCEMIC AND ANTINOCICEPTIVE ACTIVITY EVALUATION OF AMORPHOPHALLUS CAMPANULATUS CORMS / MD MIZANUR RAHAMAN, MOHAMMED MEHDI HASAN, IMRUL HASAN BADAL, AUDITI SWARNA, SHAHNAZ RAHMAN, MOHAMMED RAHMATULLAH / Int J Pharm Pharm Scie, Vol 6, Suppl 2: 613-616
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Beneficial effect of Amorphophallus paeoniifolius tuber on experimental ulcerative colitis in rats. / Dev Yadu Nandan Y N, Sharma Garima G, Kumar Dharmendra D, Lomash Vinay, Jadhav D / Pharmaceutical Biology 2017; 55(1) / DOI: https://doi.org/10.1080/13880209.2016.1226904
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ANTIHYPERLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF AMORPHOPHALLUS PAEONIIFOLIUS TUBER IN TRITON WR 1339 INDUCED HYPERLIPIDEMIC RATS / Arti Gautam, Pritt Verma, Shravan Kumar Paswan, Ila Shukla, and Ch. V. Rao / INTERNATIONAL JOURNAL OF PHARMACOGNOSY / DOI: 10.13040/IJPSR.0975-8232.IJP
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Curative effect of Amorphophallus paeoniifolius tuber on experimental hemorrhoids in rats.
/ Yadu Nandan YN Dey, Manish M MM Wanjari, Dharmendra D Kumar, Vinay V Lomash, Ankush D AD Jadhav / Journal of Ethnopharmacology, Nov 2016; Vol 192: pp 183-191 / DOI: https://doi.org/10-1016/j.jep.2016.07.042
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A Review of Multiple Potential of Aroid: Amorphophallus paeonifolius / Anuradha Singh, Neeraj Wadhwa / Int J Pharm Sci Rev Res., Jan-Feb 2014; 24(1): pp 55-60 / ISSN: 0976-044X
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Isolation and characterization of secondary metabolite from Amorpophallus paeonifolius for hepatoprotective activity / Sharsty R A, Biradar S M, Mahadevan K M, Habbu P V / Research Journal of Pharmaceutical, Biological, and Chemical Sciences, 2010; 1(4): pp 429-437 / ISSN: 0975-8585
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Optimization of Elephant Foot Yam (Amorphophallus paeoniifolius) Extract Syrup Formula as a Nutritive Antioxidant Drink / Inake Putri, Antonius Hintono, Siti Susanti / International Journal of Sustainable Agricultural Research, March 2018; 5(1): pp 1-9 / DOI: 10.18488/journal.70.2018.51.1.9
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In vitro antioxidant activity of Amorphophallus paeoniifolius tuber: Effect of extraction solvents / Tanaya Ghosh, Prasenjit Mitra, Prasanta Kumar Mitra / J Pharm Adv Res., 2019; 2(5): pp 553-556 / eISSN: 2581-6160
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Beneficial effect of standardized extracts of Amorphophallus paeoniifolium tuber and its active constituents on experimental constipation in rats / Yadu Nandan Dey, Manish M Wanjari, Bhavana Srivastava, Deepti Sharma, Sudesh Gaidhani et al / Heliyon, May 2020, 6(5) / e04023
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Edible Tuber Amorphophallus paeoniifolius (Dennst.) Extract Induces Apoptosis and Suppresses Migration of Breast Cancer Cells / Munmi Majumder, Manoj Sharma, Siddhartha Maiti and Rupak Mukhopadhyay / Nutrition and Cancer, 2020 / DOI: https://doi.org/10.1080/01635581.2020.1830127
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Green Synthesis, Characterization and Antibacterial Activity of Silver Nanoparticles Using Amorphophallus paeoniifolius Leaf Extract /M Gomathi, A Prakasam, P V Rajkumar / Journal of Cluster Science, 2019; 30: pp 995-1001
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In vitro phytochemical screening and antibacterial activity of Amorphophallus paeoniifolius (Dennst. Nicolson) against some human pathogens / Peraman Muthukumaran, Nachimuthu Saraswathy, Palanikumar Indumathi et al / Journal of Chemical and Pharmaceutical Research, 2016; 8(2): pp 388-392 / ISSN: 0975-7384
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Is elephant foot yam (Amorphophallus peoniifolius) tuber detrimental to patients with diabetes? (Or a myth?) / Shaikh Shahinur Rahman / Research & Reviews, Sept-Oct 2020; 14(5): pp 015-1016 /
DOI: https://doi.org/10.1016/j.dsx.2020.06.052
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Evaluation of anticancer property of amblyone from Amorphophallus paeoniifolius (elephant foot yam) using in silico analysis / Latha M S, Alex Anju, John Divya Mariam / Journal of Advanced Scientific Research, 2020; 11(Suppl): pp 184-189
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Assessment of antibacterial activity of Amorphophallus paeoniifolius tuber and its peel extracts / Venkata Narasimha Kadali, Tadi Ramesh, Sudhakara Rao Pola and B V Sandeep / Tropical Plant Research, 2016; 3(1): pp 172-175 / eISSN: 2349-1183, pISSN: 2349-9265
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Efficacy of stem of Amorphophallus paeoniifolius on antihyperlipidemic activity / K Bavithra, V Paheerathan, R Sivakaneshan / World Journal of Pharmaceutical Research, 2017; 6(12): pp 75-84 / ISSN: 2277-7105 / DOI: 10.20959/wjpr201712-9412
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Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats / Shaikh Shahinur Rahman, Hussain Mohammad Salaudin, Mahfuzur Rahman, Mir Mohammad Muhsin, Shakh M A Rouf / Biochemistry and Biophysics Reports, March 2021; Vol 27 / DOI: https://doi.org/10.1016/j.bbrep.2021.100917
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Amorphophallus paeoniifolius corm: A potential source of peroxidase for wide applications / Shika Singh, Rajani Singh, Ambuj Bhushan Jha, Amarendra Narayan Misra and Pallavi Sharma / International Journal of Food Properties, 2017; 20(11) / DOI: https://doi.org/10.1080/10942912.2016.1247363
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Anti-Inflammatory activity of methanolic extract of Amorphophallus paeoniifolius and its possible mechanism / Shankhajit De, Dey Y N, Ghosh A K / International Journal of Pharma and Bio Sciences, 2010; 1(3) / ISSN: 0975-6299
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Mutagenicity of Amorphophallus paeoniifolius corm aqueous extracts using allium toxicity assay / Joanna Nicole G Baniqued, Orlex B Yilano / Proceedings International Scholars Conference, 4(1) /
DOI: https://doi.org/10.35974/usc.v4i1.18
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Plants used by the tribes for the treatment of digestive system disorders in Wayanad district, Kerala / A G Devi Prasad, T B Shyma, M P Raghavendra / Journal of Applied Pharmaceutical Science, Aug 2013; 3(8): pp 171-175 / ISSN: 2231-3354 / DOI: 10.7324/JAPS.2013.3830
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Phylogenetic trends in the evolution of inflorescence odours in Amorphophallus / Geoffrey C Kite, Wilbert L A Hetterscheid / Phytochemistry, Oct 2017; Vol 142: pp 126-142 / DOI: 10.1016/j.phytochem.2017.06.006
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A potential biopesticide from Amorphophallus paeoniifolius to increase the shelf life of stored food grains / Gayathri Vijayakumar, Mohan Kumar B S / Food Processing and Preservation /
DOI: https://doi.org/10.1111/jfpp.15121
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Gastrokinetic activity of Amorphophallus paeoniifolius tuber in rats / Yadu Nandan Dey, Shivani Mahor, Dharmendra Kumar, Manish Wanjari, Sudesh Gaidhani, and Ankush Jadhay / Journal of Intercultural Ethnopharmacology, Jam-Feb 2016; 5(1): pp 36-42 / DOI: 10.5455/jice.20151211063810 / PMID: 27069720

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