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Family Fabaceae
Tayum
Indigofera suffruticosa Miller
ANIL INDIGO

Ye qing shu

Scientific names Common names
Indigofera suffruticosa Miller Pauai (Iv.)
Indigofera anil Linn. Tagum (S. L. Bis.)
Indigofera argentea Blanco Tagun (P. Bis.)
  Tayom (Ilk.)
  Tayon (Ilk.)
  Tayum (Ilk., Tag., P. Bis., C. Bis.)
  Yagum (Bis.)
  Anil de pasto (Span.)
  Anil indigo (Engl.)
  Wild indigo (Engl.)
  Small-leaved indigo (Engl.)
  Ye qing shu (Engl.)
Quisumbing's compilation lists three Indigofera species (1) Indigofera hirsuta Linn. taiuman, and (2) Indigofera tinctoria Linn, tina-tinaan, and (3) Indigofera suffruticosa Miller, tayum - with a confusing crossover attributions of common names in other compilations.

Botany
Tayum is an erect, branched, half-woody plant, 1 meter or less in height. Stems are sparsely covered with short, appressed hairs. Leaves are 5 to 8 centimeters long. Leaflets are 9 to 11, oblong to elliptic-oblong, 1 to 2 centimeters in length, pale, and appressed-hairy beneath. Flowers are red, about 5 millimeters long, borne on axillary and solitary racemes 2 to 3 centimeters in length. Pods are numerous, crowded, reflexed, strongly curved, 1 to 1.5 centimeters long, containing 6 to 8 seeds.

Distribution
- In waste places in and about towns, locally abundant, occasionally cultivated, from the Batan Islands and northern Luzon to Mindanao.
- Pantropic.

Constituents
- Indigo: One of the sources of natural indigo; along with Indigofera tinctoria, represents the chief indigo of commerce.

Properties
- Considered febrifuge, vulnerary, purgative, antispasmodic, diuretic, stomachic.

Parts used
Seeds, roots, leaves.

Uses

Folkloric
Bruisedleaves used as anodyne in warm baths.
Decoction of leaves used as sudorific.
Aztecs used the seeds for urinary diseases and ulcers.
Poultice of seeds applied to the head for fever.
Whole plant used as a remedy for syphilis.
Used for epilepsy.
In Brazil, a reputed remedy for snake bites.
In the U.S., applied to stings of bees and other insects.
In Mexico, leaves used as cataplasm or decoction, applied to childrens forehead for fever, or other painful areas.
Powdered seeds used for ulcers.
Others
- Manure: In Malaya and Java, used to be cultivated as green manure.
- Dye: Source of indigo dye.
- Cover crop: Also used as a perennial cover crop for coffee.
- Roots and seeds, powdered, decoction or infused in rum, used for destroying vermin upon the human body.


Studies
Antibacterial / Antifungal:
Studies of various extracts of Indigofera suffruticosa showed the aqueous extract of leaves with strong inhibitory activity against S aureus and against dermatophyte strains - Trichophyton rubrum and Microsporum canis. Results suggests aqueous extracts of leaves of IS by infusion can be used as treatment of dermatophytic skin diseases.
Mutagenicity: Flavonoid and alkaloid fractions showed mutagenicity. The alkaloid fraction contained indigo and indirubin; indigo was found mainly responsible for the mutagenic activity. Results also suggest that indiscriminate use of homemade preparations of the plant can be dangerous to heatlh, and that natural products, like synthetic medicines, need to be evaluated with regard pharmacologic properties, toxicity, dosage and safety.
Antitumor: Aqueous extracts of leaves of Indigofera suffruticosa showed a tumor reducing activity on Sarcoma 180 in mice. The actual mechanism is not known, but the antitumor activity may be due to its interference with cell development.
Embryotoxicity: In a study of the aqueous extract of leaves of IS for adverse effects in preimplantation mouse embryos showed embryotoxicity effects that suggest use of AELIs may be hazardous to humans who make use of it in folk medicine.

Antimycobacterial: A study evaluated the antimycobacterial activity and innate immune response of methanol and dichlormethane extracts of I. suffruticosa. Results showed induction of innate immune response through the production of high levels of NO and TNF-a (p<.001) suggesting a possible important immunological role in TB control once macrophage activity is induced.
Mosquitocidal / Repellent / Embryotoxicity: A study of aqueous extract of I. suffruticosa leaves showed repellent activity, specific embryotoxicity, and general growth retardation in Aedes aegypti.
Immunostimulatory / Cytotoxic Activities: Study of an alkaloidal fraction and a pure alkaloid indo showed cytotoxic activity against both breat and lung adenocarcinoma cell lines. Results showed immunostimulatory and cytotoxic activity of IS, enhancing macrophage function and contributing to host defense against tumors.
Gastroprotective / Ulcer Healing: Study of methanolic extract of IS in a rodent experimental model investigated ulcer healing and gastroprotective effects via mucus and gastric secretion. Results showed the AcF accelerated ulcer healing, acting as gastroprotective agent stimulating prostaglandin, mucus and HSP70.

Availability
Wild-crafted.

Last Update August 2011

IMAGE SOURCE: Public Domain / File:Koeh-076.jpg / Franz Eugen Köhler, Köhler's Medizinal-Pflanzen / 1897 / Wikipedia
OTHER IMAGE SOURCE: PIndigofera suffruticosa / Fruit at Paia, Maui / Forest and Kim Starr - Plants of Hawaii / Creative Commons Attribution 3.0 License / alterVISTA

Additional Sources and Suggested Readings
(1)
Antimicrobial Activity of Indigofera suffruticosa / Sônia Pereira Leite, Jeymesson Raphael Cardoso Vieira, Paloma Lys de Medeiros et al / Evid Based Complement Alternat Med. 2006 June; 3(2): 261–265.
(2)
Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts / Tamara Regina Calvo, Cassia Regina Primila Cardoso et al / eCAM, doi:10.1093/ecam/nep123
(3)
Indigofera suffruticosa: An Alternative Anticancer Therapy / Jeymesson Raphael Cardoso Vieira, Ivone Antônia de Souza et al / Evid Based Complement Alternat Med. 2007 September; 4(3): 355–359.
(4)
Embryotoxicity in vitro with extract of Indigofera suffruticosa leaves / Sônia Pereira Leite, Paloma Lys de Medeiros, Eliete Cavalcanti da Silva et al /
Reproductive Toxicology, Volume 18, Issue 5, July 2004, Pages 701-705 / doi:10.1016/j.reprotox.2004.04.004
(5)
Antimycobacterial activity of Indigofera suffruticosa with activation potential of the innate immune system / Camila B. de A. Carli, Marcela B. Quilles, Daniele C. G. Maia et al / Pharmaceutical Biology, August 2010, Vol. 48, No. 8 , Pages 878-882 / (doi:10.3109/13880200903303471)
(6)
Oviposition and Embryotoxicity of Indigofera suffruticosa on Early Development of Aedes aegypti (Diptera: Culicidae) / Jaymesson Raphael Cardoso Vieira, Roberta Maria Pereira Leita et al / Evid Based Complement Alternat Med. 2012; 2012: 741638 / doi: 10.1155/2012/741638
(7)
mmunostimulatory and cytotoxic activities of Indigofera suffruticosa (Fabaceae). / Flavia C M Lopes, Tamara R Calvo, Lucas L Colombo, Wagner Vilegas, Iracilda Z Carlos / Nat Prod Res. 2011 Jan 1, 1-11 21656418
(8)
Indigofera suffruticosa Mill as new source of healing agent: Involvement of prostaglandin and mucus and heat shock proteins / Anderson Luiz-Ferreira, Maira Cola, Victor Barbastefano, Elisangela Farias-Silva et al / Journal of ethnopharmacology. (impact factor: 2.32) 05/2011; DOI: 10.1016/j.jep.2011.05.006


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