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Family Annonaceae
Hilagak
Uvaria rufa
Blume
CARABAO'S TEATS
Xiao hua zi yu pan

Scientific names  Common names 
Uvaria rufa Blume Allagat (Ilk.)
Uvaria Solanifolia Presl Batag-kabalang (Bik.)
Unona setigera Blanco Hilagak (Tag.)
Uvaria ridleyi King Hinlalagak (Tag.)
? Uvaria purpurea Blume Iniu (Sbl.)
  Pedped (Ilk.)
` Susung-damulag (Pamp.)
  Susung-kabayo (Tag.)
  Susung-kalabau (Tag.)
  Xiao hua zi yu pan (Chin.)
  Carabao's teats (Engl.)
Susung-kalabau is a local name shared by (1) Hilagak, Uvaria rufa, and (2) Susong-damulog, Artabotrys suaveolens.

Botany
A climbing shrub, 5 to 6 meters high. The younger and lower surfaces of the leaves are hairy, with rusty short hairs. Leaves are borne on very short stalks, oblong-ovate to oblong-lanceolate, 8 to 16 cm long, with pointed tips and rounded or heart-shaped bases. Flowers are extra-axillary, solitary, two or three in depauperate cymes, 1.5 to 2 cm in diameter. The fruit is fleshy and red when mature.

Distribution
- In thickets in low and medium altitudes from nothern Luzon to Palawan and Mindanao.
- Also occurs in the Malaysia, Laos, Indonesia, India, Cambodia and Thailand.

Chemical constituents
• The bark contains an alkaloid. The active principle is parasympathetic of the atropine group with activity similar to artabotrine of Marañon.
• Study yielded an oil rich in sesquiterpenes in which the principal component was alpha-humulene (50%). Also, benzyl benzoate (5%).

Parts utilized
Roots

Uses
Edibility
Fruits are edible, with a tart and sweet flavor.
Folkloric
Alcoholic tincture of the roots used as an ecbolic (promoting labor by increasing uterine contractions.
Others
Handicraft: Wood used as substitute for rattan in making furniture and handicrafts.


Studies
Essential Oil / Sesquiterpene:
Uvaria rufa yielded an oil rich in sesquiterpene, in which the principle component as [alpha]-humulene (50%). Benzyl benzoate was also present at 5%.
Flavonoid Glycosides / Advanced Glycation End-Products Inhibition / Anti-Diabetic: Study yielded five flavonol glycosides: rutin, isoquercitrin, kaempferol 3-O-ß-galactopyranoside, astragalin, isoquercitrin-6-acetate. 2 of the compounds showed an ability to inhibit the formation of AGEs in the bovine serum albumin-glucose assay. AGEs contribute to the development and progression of diabetic complications and aging.
Polyoxygenated Cyclohexene Derivatives: Study yielded four new polyoxygenated cyclohexene derivatives, uvarirufone A, uvarirufols A-C, along with 10 known compounds from the aerial parts of U. rufa.

Availability
Wild-crafted. 

Last Update July 2011

GRAPHIC: Digitally modified image from Minor Products of Philippine Forests / Vol 2 / Wild Food Plants of the Philippines / William H Brown / Figure 26 / Uvaria rufa (susung-kalabau) / 1920

Additional Sources and Suggested Readings
(1)
Essential Oils from the Leaves of Some Queensland Annonaceae / by Brophy, Joseph, Goldsack, Robert, Forster, Paul / Journal of Essential Oil Research • Mar/Apr 2004
(2)
Highly oxygenated cyclohexene metabolites from Uvaria rufa / Florie A. Tudla et al / Biochemical Systematics and Ecology, Volume 35, Issue 1, January 2007, Pages 45-47 / doi:10.1016/j.bse.2006.08.006
(3)
Flavonoid glycosides from the leaves of Uvaria rufa withadvanced glycation end-products inhibitory activity / Khanittha Deepra et al / Thai J. Pharm. Sci. 33 (2009) 84-90

(4)
Polyoxygenated Cyclohexene Derivatives from Uvaria rufa / Chuan-Rui Zhang, Sheng-Ping Yang et al / Helvetica Chimica Acta, Vol 89, Issue 7, pages 1408–1416, July 2006 / DOI: 10.1002/hlca.200690140


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